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Results for "

lysosomal alpha-glucosidase

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Inhibitory Antibodies

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-E70183
    Lysosomal α-Glucosidase

    EC:3.2.1.20; GAA

    		 Biochemical Assay Reagents Others
    Lysosomal α-Glucosidase (EC:3.2.1.20) is a γ-amylase with specificity for glycogen and several natural and synthetic oligoglucosides .
    Lysosomal α-Glucosidase
  • HY-178202
    5-C-phenethyl-DNJ

    		Glycosidase Metabolic Disease
    5-C-phenethyl-DNJ is a selective α-glucosidase GAA inhibitor, with its Ki value for rhGAA being 0.81 μM. 5-C-phenethyl-DNJ exhibits extremely high selectivity for GANAB, GBA1, and GBA2. 5-C-phenethyl-DNJ can be used for the study of Pompe disease .
    5-C-phenethyl-DNJ
  • HY-108828
    Alglucosidase alfa

    rhGAA

    		 Glycosidase Metabolic Disease
    Alglucosidase alfa (rhGAA) is a hydrolytic lysosomal glycogen-specific recombinant human α-glucosidase. Alglucosidase alfa can be used for Pompe disease research .
    Alglucosidase alfa
  • HY-154995
    N-4′-(p-Trifluoromethylphenyl)butyl-DAB

    		Glycosidase Infection
    N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) is an agonit of lysosomal acid α-glucosidase (GAA). N-4′-(p-Trifluoromethylphenyl)butyl-DAB increases intracellular GAA activities dose-dependently, in Pompe patient's fibroblasts with the M519V mutation .
    N-4′-(p-Trifluoromethylphenyl)butyl-DAB
  • HY-P99803
    Clervonafusp alfa

    VAL-1221

    		 Glycosidase Others
    Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research .
    Clervonafusp alfa
  • HY-182037
    Multi-target kinase-IN-9

    		DNA/RNA Synthesis Pyruvate Kinase Cancer
    Multi-target kinase-IN-9 is a multi-target enzyme inhibitor with antiproliferative and antiangiogenic activities, and exhibits remarkable selectivity against hepatocellular carcinoma cells. By broadly binding to the active sites or ATP-binding regions of multiple key enzymes including DNA polymerase β, Pyruvate Kinase M2 (PKM2), Multi-target kinase-IN-9 comprehensively disrupts DNA repair and replication, glycolysis, chromatin dynamics and transcriptional programs, and blocks the self-renewal of cancer stem cells. Multi-target kinase-IN-9 induces genomic instability, lysosomal dysfunction and autophagic flux impairment, thereby triggering tumor cell death, effectively inhibiting tumor proliferation, invasion, metastasis and angiogenesis, and significantly reducing tumor volume in xenograft models. Multi-target kinase-IN-9 is applicable to hepatocellular carcinoma-related research .
    Multi-target kinase-IN-9

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