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Results for "

p63

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

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Antibodies

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  • HY-P700976
    CKAP4 Protein, Human (282a.a, His)

    Climp-63; p63; CLIMP-63; ERGIC-63;

    		Human E. coli
    CKAP1/TBCB Protein plays a crucial role in cellular functions, anchoring the endoplasmic reticulum to microtubules for structural organization. Moreover, it serves as a high-affinity epithelial cell surface receptor for APF/antiproliferative factor, transmitting antiproliferative signals. This dual functionality underscores CKAP1/TBCB's significance in both intracellular structural dynamics and cellular signaling processes. CKAP1/TBCB Protein Protein, Human (282a.a, His) is the recombinant human-derived CKAP1/TBCB protein protein, expressed by E. coli, with N-His labeled tag. The total length of CKAP1/TBCB Protein Protein, Human (282a.a, His) is 475 a.a., with molecular weight of 53.66 kDa.
  • HY-P73734
    p63/TP73L Protein, Human (sf9, His-GST)

    Tumor protein 63; p63; CUSP; Tp63; p73L

    		 Human Sf9 insect cells
    p63/TP73L Protein, a sequence-specific DNA binding transcriptional regulator, exhibits diverse activities through its isoforms. Isoform 2 activates RIPK4 transcription, and the protein's engagement with TP73/p73 initiates p53/TP53-dependent apoptosis in response to genotoxic stress. p63 contributes to Notch signaling, potentially inducing JAG1 and JAG2, and influences epithelial morphogenesis. The balance between DeltaN-type and TA*-type isoforms governs epithelial stem cell compartments, impacting epithelial stratification. Additionally, p63 is essential for limb formation and regulates the p21 promoter transcription. p63/TP73L Protein, Human (sf9, His-GST) is the recombinant human-derived p63/TP73L protein, expressed by Sf9 insect cells, with N-His, N-GST labeled tag. The total length of p63/TP73L Protein, Human (sf9, His-GST) is 680 a.a., with molecular weight of ~125 kDa.
  • HY-P701803
    MAPK4 Protein, Human (Sf9, His, GST)

    MAPK4; Mitogen-activated protein kinase 4; MAP kinase 4; MAPK 4; Extracellular signal-regulated kinase 4; ERK-4; MAP kinase isoform p63; p63-MAPK

    		 Human Sf9 insect cells
    MAPK4, an atypical MAPK protein, phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5, forming a complex with intricate phosphorylation events. Interaction with MAPKAPK5 leads to ERK3/MAPK6 phosphorylation at Ser-189, activating MAPKAPK5, which reciprocally phosphorylates ERK3/MAPK6. The specific cellular role of this interplay, while unclear, suggests ERK3's potential involvement in promoting entry into the cell cycle. MAPK4 Protein, Human (Sf9, His, GST) is the recombinant human-derived MAPK4 protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAPK4 Protein, Human (Sf9, His, GST) is 586 a.a., .

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