CKAP4 Protein, Human (282a.a, His)

CKAP1/TBCB Protein plays a crucial role in cellular functions, anchoring the endoplasmic reticulum to microtubules for structural organization. Moreover, it serves as a high-affinity epithelial cell surface receptor for APF/antiproliferative factor, transmitting antiproliferative signals. This dual functionality underscores CKAP1/TBCB's significance in both intracellular structural dynamics and cellular signaling processes. CKAP1/TBCB Protein Protein, Human (282a.a, His) is the recombinant human-derived CKAP1/TBCB protein protein, expressed by E. coli, with N-His labeled tag. The total length of CKAP1/TBCB Protein Protein, Human (282a.a, His) is 475 a.a., with molecular weight of 53.66 kDa.

CKAP1/TBCB Protein assumes a crucial role in cellular functions by mediating the anchoring of the endoplasmic reticulum to microtubules, contributing to the structural organization of the cell. Additionally, it functions as a high-affinity epithelial cell surface receptor for the low molecular weight sialoglycopeptide APF/antiproliferative factor, playing a pivotal role in transducing APF's antiproliferative signaling within cells. This dual functionality underscores CKAP1/TBCB's significance in both intracellular structural dynamics, through its involvement in endoplasmic reticulum anchoring, and cellular signaling processes, as an essential mediator of APF-induced antiproliferative effects at the cell surface.

Human

E. coli

N-His

Q07065 (H128-V602)

10970  [NCBI]

53.66 kDa

Greater than 90 % as determined by SDS-PAGE.

<1 EU/μg, determined by LAL method.