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Results for "

triazole scaffold

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161943
    NEU3-IN-1

    		Influenza Virus Neurological Disease
    NEU3-IN-1 (compound 963) is a NEU3 inhibitor (Ki: 0.12 μM; IC50: 0.31 μM) based on the 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) scaffold and is a C9 biphenylcarbamate derivative. NEU is a human neuraminidase with 4 isozymes; NEU3-IN-1 is an important tool for studying the function of NEU3 isozymes; its amide and triazole linker analogs are selective for NEU1 and NEU4 isozymes, respectively .
    NEU3-IN-1
  • HY-146079
    Antifungal agent 31

    		Fungal Infection
    Antifungal agent 31 (compound 12) is a potent and orally active triazole antifungal agents with a pyrrolotriazinone scaffold. Antifungal agent 31 shows antifungal activity against Candida spp. and filamentous fungi. Antifungal agent 31 significantly reduced mortality rates and kidney fungal burden in two murine models of lethal systemic infections .
    Antifungal agent 31
  • HY-181824
    Cholera toxin-IN-1

    		Bacterial Infection
    Cholera toxin-IN-1 is a potent competitive inhibitor of cholera toxin B subunit (CTB) with an IC50 value of 11.78 μM. Cholera toxin-IN-1 forms stable hydrogen bonds and hydrophobic interactions. Cholera toxin-IN-1 competitively blocks the binding of CTB to GM1 ganglioside. Cholera toxin-IN-1 can be used for the research of cholera .
    Cholera toxin-IN-1

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