1. GPCR/G Protein
  2. TSH Receptor
  3. TSHR antagonist S37

TSHR antagonist S37 

Cat. No.: HY-129995B
Handling Instructions

TSHR antagonist S37 is a selective and competitive thyrotropin receptor (TSHR) antagonist. TSHR antagonist S37 is the racemate of TSHR antagonist S37a.

For research use only. We do not sell to patients.

TSHR antagonist S37 Chemical Structure

TSHR antagonist S37 Chemical Structure

CAS No. : 1217616-61-9

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Description

TSHR antagonist S37 is a selective and competitive thyrotropin receptor (TSHR) antagonist. TSHR antagonist S37 is the racemate of TSHR antagonist S37a[1].

IC50 & Target

TSHR[1]

In Vitro

TSHR antagonist S37 reduces also cAMP activation induced by the small molecule agonist C2[1].
TSHR antagonist S37 (10-100 µM) does not affect cell viability in the concentration range for the Hek293T-TSHR cell line[1].

Molecular Weight

460.57

Formula

C₂₅H₂₀N₂O₃S₂

CAS No.

1217616-61-9

SMILES

O=C(N1)SC(C2C3=CC=CC=C3)=C1SC(C2C4C56)C(C4)C6C(N(C7=CC=CC=C7)C5=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

TSHR antagonist S37TSHR antagonist S 37TSHR antagonist S-37TSH ReceptorThyrotropin receptorThyroid-stimulating hormone ReceptorTSHRInhibitorinhibitorinhibit

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TSHR antagonist S37
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