2. Apoptosis
  3. Apoptosis
  4. Vin-F03

Vin-F03 is a potent pancreatic β-cells protective agent with an EC50 of 0.27 μM. Vin-F03 effectively promotes β-cell survival and protects β-cells from STZ (HY-13753)-induced apoptosis. Vin-F03 can be used for type 2 diabetes mellitus research.

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Vin-F03

Vin-F03 Estructura química

No. CAS : 2180917-11-5

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Vin-F03 Related Antibodies

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Descripciòn

Vin-F03 is a potent pancreatic β-cells protective agent with an EC50 of 0.27 μM. Vin-F03 effectively promotes β-cell survival and protects β-cells from STZ (HY-13753)-induced apoptosis. Vin-F03 can be used for type 2 diabetes mellitus research[1].

IC50 & Target

EC50: 0.27 µM (pancreatic β-cells)[1]
Cellular Effect
Cell Line Type Value Description References
INS1(832/13) EC50
0.27 μM
Compound: Vin-F03
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
[PMID: 31918073]
Peso molecular

335.49

Fòrmula

C22H29N3
No. CAS
SMILES

[H][C@]12C3=C4CCN1CCC[C@]2(C=C(N3C5=CC=CC=C54)CNCC)CC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Pureza y Documentación
Referencias
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Vin-F03 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vin-F032180917-11-5Apoptosistype 2 diabetes mellituspancreatic β-cellsInhibitorinhibitorinhibit

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Nombre del producto:
Vin-F03
Cat. No.:
HY-147503
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