1. Protein Tyrosine Kinase/RTK
  2. TAM Receptor
    c-Met/HGFR
  3. XL092

XL092 

Cat. No.: HY-138696 Purity: 99.52%
Handling Instructions

XL092 is a potent inhibitor of the activity of Axl, Mer and C-Met kinase with IC50s of <10 nM, respectively. XL092 exhibits anti-tumor activity and has the potential for kinase-dependent diseases and conditions research.

For research use only. We do not sell to patients.

XL092 Chemical Structure

XL092 Chemical Structure

CAS No. : 2367004-54-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 233 In-stock
Estimated Time of Arrival: December 31
5 mg USD 200 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
25 mg USD 700 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

XL092 is a potent inhibitor of the activity of Axl, Mer and C-Met kinase with IC50s of <10 nM, respectively. XL092 exhibits anti-tumor activity and has the potential for kinase-dependent diseases and conditions research[1].

In Vivo

XL092 (compound 8; 3 mg/kg; iv) has a T1/2 of 5.4 hours, a CL of 43 mL/hr•kg. XL092 (3 mg/kg; po) has a T1/2 of 7.1 hours and a Cmax of 11.4 μM for rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

528.53

Formula

C₂₉H₂₅FN₄O₅

CAS No.
SMILES

O=C(C1=CC2=C(OC3=CC=C(NC(C4(CC4)C(NC5=CC=C(C=C5)F)=O)=O)C=C3)C=CN=C2C=C1OC)NC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References
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Keywords:

XL092XL 092XL-092TAM Receptorc-Met/HGFRTyro3AxlMerInhibitorinhibitorinhibit

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