α-Methyl-DL-aspartic acid

Name: α-Methyl-DL-aspartic acid
Brand: MedChemExpress
SKU: HY-W142119
Rating: 5.0 (4 reviews)

Cat. No.: HY-W142119 Purity: 99.93%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS), and also is the rate-limiting enzyme for the recycling of 1-citrulline to 1-arginine.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Custom Peptide Synthesis

α-Methyl-DL-aspartic acid 화학구조

CAS No. : 2792-66-7

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 4 publication(s) in Google Scholar

4 Publications Citing Use of MCE α-Methyl-DL-aspartic acid

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•Related Small Molecules:

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

α-Methyl-DL-aspartic acid is a specific inhibitor of argininosuccinate synthase (ASS), and also is the rate-limiting enzyme for the recycling of 1-citrulline to 1-arginine^[1].

In Vitro

α-methyl-dl-aspartic acid can significantly reduce the anti-hypertensive activity of Bj-BPP-10c in SHR^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

α-methyl-dl-aspartic acid (147 mg/kg, i.v.) can diminish the l-citrulline-induced retinal vasodilation in Wistar rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Wistar rats
Dosage:	147 mg/kg
Administration:	147 mg/kg, i.v.
Result:	Attenuated the increase of retinal arteriolar diameter induced by L-citrulline.

분자량

147.13

화학식

C₅H₉NO₄

CAS No.

2792-66-7

Appearance

Solid

Color

White to off-white

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years

*The compound is unstable in solutions, freshly prepared is recommended.

용액&용해도

In Vitro:

H₂O : 50 mg/mL (339.84 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.7967 mL	33.9836 mL	67.9671 mL
5 mM	1.3593 mL	6.7967 mL	13.5934 mL
10 mM	0.6797 mL	3.3984 mL	6.7967 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.93%

Select Batch:

Data Sheet (273 KB) SDS (393 KB)

COA (248 KB) HNMR (245 KB) RP-HPLC (195 KB) MS (69 KB)

Handling Instructions (2659 KB)

References

[1]. Asami Mori, et al. l-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo. J Pharmacol Sci. 2015 Apr;127(4):419-23. [Content Brief]

[2]. Juliano R Guerreiro, et al. Argininosuccinate synthetase is a functional target for a snake venom anti-hypertensive peptide: role in arginine and nitric oxide production. J Biol Chem. 2009 Jul 24;284(30):20022-33. [Content Brief]

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.7967 mL	33.9836 mL	67.9671 mL	169.9178 mL
	5 mM	1.3593 mL	6.7967 mL	13.5934 mL	33.9836 mL
	10 mM	0.6797 mL	3.3984 mL	6.7967 mL	16.9918 mL
	15 mM	0.4531 mL	2.2656 mL	4.5311 mL	11.3279 mL
	20 mM	0.3398 mL	1.6992 mL	3.3984 mL	8.4959 mL
	25 mM	0.2719 mL	1.3593 mL	2.7187 mL	6.7967 mL
	30 mM	0.2266 mL	1.1328 mL	2.2656 mL	5.6639 mL
	40 mM	0.1699 mL	0.8496 mL	1.6992 mL	4.2479 mL
	50 mM	0.1359 mL	0.6797 mL	1.3593 mL	3.3984 mL
	60 mM	0.1133 mL	0.5664 mL	1.1328 mL	2.8320 mL
	80 mM	0.0850 mL	0.4248 mL	0.8496 mL	2.1240 mL
	100 mM	0.0680 mL	0.3398 mL	0.6797 mL	1.6992 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.