1,2,3,5-Tetramethylbenzene  (Synonyms: Isodurene)

1,2,3,5-Tetramethylbenzene (Isodurene) is an aromatic hydrocarbon isomer of tetramethylbenzene. 1,2,3,5-Tetramethylbenzene serves as an important component of industrial organic solvents. 1,2,3,5-Tetramethylbenzene can be used in the organic synthesis of plastics and resins. 1,2,3,5-Tetramethylbenzene exhibits potential neurotoxicity, acute oral toxicity and mild skin irritation activity^[1][2].

1,2,3,5-Tetramethylbenzene has an oral LD₅₀ of 5157 mg/kg in male SD rats, and lethal doses induce toxic effects on the gastrointestinal and respiratory systems^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

134.22

C₁₀H₁₄

527-53-7

CC1=CC(=C(C)C(=C1)C)C

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Jałowiecki P, et al. Physiologically-based toxicokinetic modeling of durene (1,2,3,5-tetramethylbenzene) and isodurene (1,2,4,5-tetramethylbenzene) in humans. Int J Occup Med Environ Health. 2007;20(2):155-165.  [Content Brief]

  [2]. Lynch DW, et al. Acute toxicity of tetramethylbenzenes: durene, isodurene and prehnitene. Drug Chem Toxicol. 1978;1(3):219-230.  [Content Brief]