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  4. 2-(2-Chloroethoxy)ethanol

2-(2-Chloroethoxy)ethanol  (Synonyms: Diethylene glycol monochlorohydrin)

Cat. No.: HY-Y1066
COA
SDS
Handling Instructions Technical Support

2-(2-Chloroethoxy)ethanol (Diethylene glycol monochlorohydrin) is an unclassified residual solvent and known impurity, with an acceptance criterion of 0.10%.2-(2-Chloroethoxy)ethanol serves as a starting material in quetiapine synthesis.

For research use only. We do not sell to patients.

2-(2-Chloroethoxy)ethanol

2-(2-Chloroethoxy)ethanol Chemical Structure

CAS No. : 628-89-7

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Liquid
25 g In-stock
50 g In-stock
100 g In-stock
500 g In-stock
1 kg In-stock

* Please select Quantity before adding items.

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2-(2-Chloroethoxy)ethanol Related Antibodies

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Description

2-(2-Chloroethoxy)ethanol (Diethylene glycol monochlorohydrin) is an unclassified residual solvent and known impurity, with an acceptance criterion of 0.10%.2-(2-Chloroethoxy)ethanol serves as a starting material in quetiapine synthesis[1].

In Vitro

2-(2-Chloroethoxy)ethanol (50-1000 ppm) was selectively separated and quantified in quetiapine via a validated gas chromatography method with flame ionization detection, with the ability to detect the compound at the acceptance criterion level of 1000 ppm[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2-(2-Chloroethoxy)ethanol Related Antibodies
Molecular Weight

124.57

Formula

C4H9ClO2
CAS No.
Appearance

Liquid

SMILES

ClCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 200 mg/mL (1605.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.0276 mL 40.1381 mL 80.2762 mL
5 mM 1.6055 mL 8.0276 mL 16.0552 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 8.0276 mL 40.1381 mL 80.2762 mL 200.6904 mL
5 mM 1.6055 mL 8.0276 mL 16.0552 mL 40.1381 mL
10 mM 0.8028 mL 4.0138 mL 8.0276 mL 20.0690 mL
15 mM 0.5352 mL 2.6759 mL 5.3517 mL 13.3794 mL
20 mM 0.4014 mL 2.0069 mL 4.0138 mL 10.0345 mL
25 mM 0.3211 mL 1.6055 mL 3.2110 mL 8.0276 mL
30 mM 0.2676 mL 1.3379 mL 2.6759 mL 6.6897 mL
40 mM 0.2007 mL 1.0035 mL 2.0069 mL 5.0173 mL
50 mM 0.1606 mL 0.8028 mL 1.6055 mL 4.0138 mL
60 mM 0.1338 mL 0.6690 mL 1.3379 mL 3.3448 mL
80 mM 0.1003 mL 0.5017 mL 1.0035 mL 2.5086 mL
100 mM 0.0803 mL 0.4014 mL 0.8028 mL 2.0069 mL
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2-(2-Chloroethoxy)ethanol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-(2-Chloroethoxy)ethanol628-89-7Diethylene glycol monochlorohydrinDrug IntermediateDrug Iintermediategas chromatographyflame ionization detectionquetiapine synthesisresidual solventInhibitorinhibitorinhibit

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