2',3'-cGMP sodium (Synonyms: Guanosine 2',3'-cyclic monophosphate sodium salt)

Cat. No.: HY-N8245 Purity: 99.28%: Data Sheet
COA

SDS
Handling Instructions
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2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase.

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2',3'-cGMP sodium 화학구조

CAS No. : 15718-49-7

사이즈	재고	수량
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기
200 mg	견적 받기

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This product is a controlled substance and not for sale in your territory.

Other Forms of 2',3'-cGMP sodium:

2′,3′-cGMP triethylamine 견적 받기
2',3'-cGMP sodium (Standard) 견적 받기

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase^[1].

In Vitro

2',3'-cGMP sodium (10 nM-100 μM, 120 min) reduces the active transport of [³H]3’,5’-cGMP into inside-out vesicles from human erythrocytes^[2].
2',3'-cGMP sodium (2 μM) increases the ATPase activity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

367.19

화학식

C₁₀H₁₁N₅NaO₇P

CAS No.

15718-49-7

Appearance

Solid

Color

White to off-white

SMILES

OC[C@H]1O[C@](N2C3=C(C(N=C(N3)N)=O)N=C2)([H])[C@@]4([H])[C@]1([H])OP(O4)(O[Na])=O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

용액&용해도

In Vitro:

H₂O : 100 mg/mL (272.34 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7234 mL	13.6169 mL	27.2339 mL
5 mM	0.5447 mL	2.7234 mL	5.4468 mL
10 mM	0.2723 mL	1.3617 mL	2.7234 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

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Concentration _(final)

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Please enter the basic information of animal experiments:

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Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.28%

Select Batch:

Data Sheet (277 KB) SDS (252 KB)

COA (256 KB) HNMR (241 KB) CNMR (274 KB) RP-HPLC (197 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Sokurenko JV, et al. [Identification of 2',3'-cGMP as an intermediate of RNA catalytic cleavage by binase and evaluation of its biological action]. Bioorg Khim. 2015 Jan-Feb;41(1):37-43. Russian. [Content Brief]

[2]. Boadu E, et al. Inhibition by guanosine cyclic monophosphate (cGMP) analogues of uptake of [(3)H]3',5'-cGMP without stimulation of ATPase activity in human erythrocyte inside-out vesicles. Biochem Pharmacol. 2001 Aug 15;62(4):425-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	2.7234 mL	13.6169 mL	27.2339 mL	68.0846 mL
	5 mM	0.5447 mL	2.7234 mL	5.4468 mL	13.6169 mL
	10 mM	0.2723 mL	1.3617 mL	2.7234 mL	6.8085 mL
	15 mM	0.1816 mL	0.9078 mL	1.8156 mL	4.5390 mL
	20 mM	0.1362 mL	0.6808 mL	1.3617 mL	3.4042 mL
	25 mM	0.1089 mL	0.5447 mL	1.0894 mL	2.7234 mL
	30 mM	0.0908 mL	0.4539 mL	0.9078 mL	2.2695 mL
	40 mM	0.0681 mL	0.3404 mL	0.6808 mL	1.7021 mL
	50 mM	0.0545 mL	0.2723 mL	0.5447 mL	1.3617 mL
	60 mM	0.0454 mL	0.2269 mL	0.4539 mL	1.1347 mL
	80 mM	0.0340 mL	0.1702 mL	0.3404 mL	0.8511 mL
	100 mM	0.0272 mL	0.1362 mL	0.2723 mL	0.6808 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

2',3'-cGMP sodium Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2',3'-cGMP15718-49-7Guanosine 2',3'-cyclic monophosphateDrug IntermediateDrug IintermediatecGMPRNA catalytic cleavagebinaseInhibitorinhibitorinhibit

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2',3'-cGMP sodium (Synonyms: Guanosine 2',3'-cyclic monophosphate sodium salt)

Other Forms of 2',3'-cGMP sodium:

2',3'-cGMP sodium Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

순도&문서

References

고객리뷰

2',3'-cGMP sodium Related Antibodies

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