2,3-Indolobetulonic acid

Cat. No.: HY-134960: Data Sheet Handling Instructions
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2,3-Indolobetulonic acid (compound 2), a triterpenoid, is α-glucosidase inhibitor with an IC₅₀ of 1.8 µM.

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2,3-Indolobetulonic acid 화학구조

CAS No. : 905837-93-6

사이즈	재고	수량
1 mg	견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 mg	견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
25 mg	견적 받기 3 - 4 Weeks 4 - 5 Weeks 5 - 6 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

2,3-Indolobetulonic acid (compound 2), a triterpenoid, is α-glucosidase inhibitor with an IC₅₀ of 1.8 µM^[1].

IC₅₀ & Target^[1]

Glucosidase

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	7.6 μg/mL Compound: 7	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 18752941]
DU-145	IC₅₀	8.86 μg/mL Compound: 7	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 18752941]
HBL-100	IC₅₀	10.3 μg/mL Compound: 7	Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay	[PMID: 18752941]
K562	IC₅₀	10.05 μg/mL Compound: 7	Cytotoxicity against human K-562 cells after 72 hrs by MTT assay Cytotoxicity against human K-562 cells after 72 hrs by MTT assay	[PMID: 18752941]
MIA PaCa-2	IC₅₀	6.7 μg/mL Compound: 7	Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay	[PMID: 18752941]
NIH3T3	IC₅₀	6.9 μg/mL Compound: 7	Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay	[PMID: 18752941]
PA-1	IC₅₀	6.01 μg/mL Compound: 7	Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay	[PMID: 18752941]
SW-620	IC₅₀	5.15 μg/mL Compound: 7	Cytotoxicity against human SW620 cells after 72 hrs by MTT assay Cytotoxicity against human SW620 cells after 72 hrs by MTT assay	[PMID: 18752941]

분자량

527.78

화학식

C₃₆H₄₉NO₂

CAS No.

905837-93-6

SMILES

OC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C6=C(C7=CC=CC=C7N6)C5)C)([H])CC4)C)([H])CC3)C)C)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Khusnutdinova, Elmira F, et al. Synthesis and evaluation of 2,3-indolotriterpenoids as new α-glucosidase inhibitors. Med Chem Res 26, 2737-2742.