6-Chloro-L-tryptophan

Name: 6-Chloro-L-tryptophan
Brand: MedChemExpress
SKU: HY-W050025
Rating: 4.5 (0 reviews)

Cat. No.: HY-W050025 Purity: 99.50%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Custom Peptide Synthesis

6-Chloro-L-tryptophan 화학구조

CAS No. : 33468-35-8

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	해외재고보유	Estimated Time of Arrival: December 31
Solid
250 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	해외재고보유	Estimated Time of Arrival: December 31
10 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

6-Chloro-L-tryptophan is a Tryptophan derivative. 6-Chloro-L-tryptophan can be used as a substrate for KtzQ^[1].

In Vitro

6-Chloro-L-tryptophan (0-500 μM) exhibits no inhibitory effect on D-amino acid oxidase (DAO)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

238.67

화학식

C₁₁H₁₁ClN₂O₂

CAS No.

33468-35-8

Appearance

Solid

Color

White to gray

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

1 M NaOH : ≥ 100 mg/mL (418.99 mM)

H₂O : 50 mg/mL (209.49 mM; ultrasonic and warming and adjust pH to 12 with 1M NaOH and heat to 60°C)

DMSO : 2 mg/mL (8.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.1899 mL	20.9494 mL	41.8989 mL
5 mM	0.8380 mL	4.1899 mL	8.3798 mL
10 mM	0.4190 mL	2.0949 mL	4.1899 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.50%

Select Batch:

Data Sheet (274 KB) SDS (393 KB)

COA (251 KB) HNMR (116 KB) RP-HPLC (248 KB)

Handling Instructions (2659 KB)

References

[1]. Heemstra JR Jr, et al. Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly. J Am Chem Soc. 2008 Oct 29;130(43):14024-5. [Content Brief]

[2]. Iwasaki M, et al. A high-performance liquid chromatography assay with a triazole-bonded column for evaluation of d-amino acid oxidase activity. Biomed Chromatogr. 2016 Mar;30(3):384-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O / 1 M NaOH	1 mM	4.1899 mL	20.9494 mL	41.8989 mL	104.7471 mL
DMSO / H₂O / 1 M NaOH	5 mM	0.8380 mL	4.1899 mL	8.3798 mL	20.9494 mL
H₂O / 1 M NaOH	10 mM	0.4190 mL	2.0949 mL	4.1899 mL	10.4747 mL
	15 mM	0.2793 mL	1.3966 mL	2.7933 mL	6.9831 mL
	20 mM	0.2095 mL	1.0475 mL	2.0949 mL	5.2374 mL
	25 mM	0.1676 mL	0.8380 mL	1.6760 mL	4.1899 mL
	30 mM	0.1397 mL	0.6983 mL	1.3966 mL	3.4916 mL
	40 mM	0.1047 mL	0.5237 mL	1.0475 mL	2.6187 mL
	50 mM	0.0838 mL	0.4190 mL	0.8380 mL	2.0949 mL
	60 mM	0.0698 mL	0.3492 mL	0.6983 mL	1.7458 mL
	80 mM	0.0524 mL	0.2619 mL	0.5237 mL	1.3093 mL
	100 mM	0.0419 mL	0.2095 mL	0.4190 mL	1.0475 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.