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Results for "

BoNT/A

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111535
    BoNT-IN-2

    		Others Others
    BoNT-IN-2 (Compound 33) is a Botulinum Neurotoxin A Light Chain (BoNT/A LC) inhibitor with an IC50 of 4.5 μM .
    <em>BoNT</em>-IN-2
  • HY-18671
    BoNT-IN-1

    		Others Neurological Disease
    BoNT-IN-1 is a potent inhibitor of Botulinum neurotoxin A light chain (BoNTA LC) with IC50 of 0.9 uM.
    <em>BoNT</em>-IN-1
  • HY-14946
    Amifampridine

    3,4-Diaminopyridine

    		 Potassium Channel Neurological Disease
    Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .
    Amifampridine
  • HY-118851
    NSC-77053

    		Others Others
    NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively .
    NSC-77053
  • HY-W596782
    Chaetochromin A

    Chaetochromin

    		 Others Neurological Disease
    Chaetochromin A (Compound 1) is a fungal metabolite. Chaetochromin A shows inhibitory effect on botulinum neurotoxin serotype A (BoNT A) (IC50= 24.6 μM) .
    Chaetochromin A
  • HY-14946A
    Amifampridine phosphate

    3,4-Diaminopyridine phosphate

    		 Potassium Channel Neurological Disease
    Amifampridine (3,4-Diaminopyridine) phosphate is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine phosphate is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine phosphate increases transmitter release from neuromuscular junctions (NMJs). Amifampridine phosphate can be used for Lambert-Eaton myasthenic syndrome (LEMS) research .
    Amifampridine phosphate

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