1. Anti-infection
  2. Fungal
    Antibiotic
  3. Fluconazole mesylate

Fluconazole mesylate (Synonyms: UK 49858 mesylate)

Cat. No.: HY-B0101B
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Fluconazole (mesylate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

For research use only. We do not sell to patients.

Fluconazole mesylate Chemical Structure

Fluconazole mesylate Chemical Structure

CAS No. : 159532-41-9

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Description

Fluconazole (mesylate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. Target: Antifungal Fluconazole (mesylate) is the mesylate salt form of fluconazole, which is a triazole antifungal intended for oral treatment of superficial and systemic mycoses. In tests done in standard mycological media, the compound had minimal inhibitory concentrations against pathogenic Candida species that were usually in excess of 100 mg/l. Fluconazole inhibited branching and hyphal development in C. albicans at concentrations as low as 10(-6) M (0.3 mg/l), but miconazole and ketoconazole were still active in these tests at concentrations 100 times lower than this [1]. Oral fluconazole was not associated with a significantly increased risk of birth defects overall or of 14 of the 15 specific birth defects of previous concern. Fluconazole exposure may confer an increased risk of tetralogy of Fallot [2]. Fluconazole is predicted to be ineffective against Cryptococcus gattii in the koala as a sole therapeutic agent administered at 10 mg/kg p.o. every 12 h [3]. Clinical indications: Balanitis; Candida infection; Cryptococcus infection; Cryptococcus neoformans meningitis; Dermatomycosis; Female genital tract infection; Fungal infection; Fungal respiratory tract infection; Fungal urinary tract infection; Prophylaxis; Tinea capitis; Tinea corporis; Tinea cruris; Tinea pedis . Toxicity: Symptoms of overdose include hallucinations and paranoid behavior.

Clinical Trial
Molecular Weight

402.38

Formula

C₁₄H₁₆F₂N₆O₄S

CAS No.

159532-41-9

SMILES

FC1=CC=C(C(O)(CN2C=NC=N2)CN3C=NC=N3)C(F)=C1.CS(=O)(O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

FluconazoleUK 49858UK49858UK-49858FungalAntibioticInhibitorinhibitorinhibit

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Fluconazole mesylate
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HY-B0101B
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