N-(5-Aminopentyl)acetamide  (Synonyms: Monoacetylcadaverine)

N-(5-Aminopentyl)acetamide is the acetylated form of the polyamine cadaverine.

Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups which ubiquitously exists in all living organisms from bacteria to higher animals. The critical step of polyamine biosynthesis generally includes the amino acid-decarboxylating reaction to produce the primary diamines, such as cadaverine from lysine. Synthesized polyamines are implicated in a wide variety of cytoplasmic reactions such as DNA replication and protein synthesis, and are essential for proper growth and proliferation of the organisms^[1]. Cadaverine is a linear molecule that terminate at both ends with an amine functional group. These functional groups confer to the molecules multiple positive charges at physiological pH. Cadaverine is produced through the action of basic amino acid decarboxylases and is found associated with the outer membrane^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

144.21

Liquid

C₇H₁₆N₂O

32343-73-0

CC(NCCCCCN)=O

Room temperature in continental US; may vary elsewhere.

• [1]. Kojima S, et al. Molecular basis for the maintenance of envelope integrity in Selenomonas ruminantium:cadaverine biosynthesis and covalent modification into the peptidoglycan play a major role. J Nutr Sci Vitaminol (Tokyo). 2012;58(3):153-60.  [Content Brief]

  [2]. Dela Vega AL, et al. Polyamines decrease Escherichia coli outer membrane permeability.  [Content Brief]