N-(5-Aminopentyl)acetamide
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N-(5-Aminopentyl)acetamide is the acetylated form of the polyamine cadaverine.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 32343-73-0
- Formula: C7H16N2O
- Molecular Weight:144.21
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Microbial Metabolite |
Human Endogenous Metabolite |
Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups which ubiquitously exists in all living organisms from bacteria to higher animals. The critical step of polyamine biosynthesis generally includes the amino acid-decarboxylating reaction to produce the primary diamines, such as cadaverine from lysine. Synthesized polyamines are implicated in a wide variety of cytoplasmic reactions such as DNA replication and protein synthesis, and are essential for proper growth and proliferation of the organisms[1]. Cadaverine is a linear molecule that terminate at both ends with an amine functional group. These functional groups confer to the molecules multiple positive charges at physiological pH. Cadaverine is produced through the action of basic amino acid decarboxylases and is found associated with the outer membrane[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 32343-73-0
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Appearance Liquid (Density: 0.938±0.06 g/cm3)
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Molecular Weight 144.21
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Formula C7H16N2O
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Color Colorless to light yellow
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SMILES
CC(NCCCCCN)=O
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Synonyms
Monoacetylcadaverine
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 175 mg/mL (1213.51 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Kojima S, et al. Molecular basis for the maintenance of envelope integrity in Selenomonas ruminantium:cadaverine biosynthesis and covalent modification into the peptidoglycan play a major role. J Nutr Sci Vitaminol (Tokyo). 2012;58(3):153-60. [Content Brief]
[2]. Dela Vega AL, et al. Polyamines decrease Escherichia coli outer membrane permeability. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.9343 mL | 34.6717 mL | 69.3433 mL | 173.3583 mL |
| 5 mM | 1.3869 mL | 6.9343 mL | 13.8687 mL | 34.6717 mL | |
| 10 mM | 0.6934 mL | 3.4672 mL | 6.9343 mL | 17.3358 mL | |
| 15 mM | 0.4623 mL | 2.3114 mL | 4.6229 mL | 11.5572 mL | |
| 20 mM | 0.3467 mL | 1.7336 mL | 3.4672 mL | 8.6679 mL | |
| 25 mM | 0.2774 mL | 1.3869 mL | 2.7737 mL | 6.9343 mL | |
| 30 mM | 0.2311 mL | 1.1557 mL | 2.3114 mL | 5.7786 mL | |
| 40 mM | 0.1734 mL | 0.8668 mL | 1.7336 mL | 4.3340 mL | |
| 50 mM | 0.1387 mL | 0.6934 mL | 1.3869 mL | 3.4672 mL | |
| 60 mM | 0.1156 mL | 0.5779 mL | 1.1557 mL | 2.8893 mL | |
| 80 mM | 0.0867 mL | 0.4334 mL | 0.8668 mL | 2.1670 mL | |
| 100 mM | 0.0693 mL | 0.3467 mL | 0.6934 mL | 1.7336 mL |
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