- Natural Products
- Plants
- Moraceae
- Maclura pomifera (Raf.) Schneid.
Maclura pomifera (Raf.) Schneid.
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Maclura pomifera (Raf.) Schneid. (5)
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- Formula: C20H18O5
- Molecular Weight: 338.35
6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells.
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- Formula: C20H16O5
- Molecular Weight: 336.34
Derrone, a prenylated isoflavones, is an Aurora kinase inhibitor, with IC50 values of 6 and 22.3 μM against Aurora B and Aurora A, respectively. Derrone shows anti-tumor activity.
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