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Cat. No.: HY-N2732

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6-Prenylapigenin

(Synonyms: 6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin)

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6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells.

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Pureté: 98.0%
CAS No.: 68097-13-2
Formule: C₂₀H₁₈O₅
Masse moléculaire:338.35

Stockage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

6-Prenylapigenin Chemical Structure

CAS No.: 68097-13-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	28.88 μM Compound: 4	Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 33609662]
HepG2	IC₅₀	>40 μM Compound: 4	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 33609662]
MCF7	IC₅₀	32.41 μM Compound: 4	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 33609662]
NCI-H460	IC₅₀	38.49 μM Compound: 4	Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell proliferation by MTT assay Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 33609662]

In Vitro

6-Prenylapigenin (compound 2) shows cytotoxicity on different cancer cell lines with IC₅₀ values of 1.7 μM, 11.2 μM, and 13.8 μM on MCF-7, PF-382, and Caski cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 68097-13-2
Appearance Solid
Masse moléculaire 338.35
Formule C₂₀H₁₈O₅
Color White to yellow
SMILES

OC1=C2C(OC(C3=CC=C(O)C=C3)=CC2=O)=CC(O)=C1C/C=C(C)/C
Synonyms

6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin
Structure Classification
- Flavonoids
- Flavones
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kuete V, et al. Cytotoxicity and mode of action of four naturally occuring flavonoids from the genus Dorstenia: gancaonin Q, 4-hydroxylonchocarpin, 6-prenylapigenin, and 6,8-diprenyleriodictyol. Planta Med. 2011 Dec;77(18):1984-9. [Content Brief]

[2]. Sang-Jun Lee, et al. Prenylated flavonoids from Maclura pomifera. Phytochemistry. Vol. 49, No. 8, pp. 2573-2577, 1998.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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