2. Natural Products
  3. Plants Flavonoids
  4. Moraceae Flavones
  5. Maclura pomifera (Raf.) Schneid.
  6. 6-Prenylapigenin

6-Prenylapigenin  (Synonyms: 6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin)

Cat. No.: HY-N2732 Purity: 98.0%
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6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells.

For research use only. We do not sell to patients.

6-Prenylapigenin

6-Prenylapigenin Chemical Structure

CAS No. : 68097-13-2

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Based on 1 publication(s) in Google Scholar

6-Prenylapigenin Related Antibodies

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Description

6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells[1][2].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
28.88 μM
Compound: 4
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
HepG2 IC50
> 40 μM
Compound: 4
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
MCF7 IC50
32.41 μM
Compound: 4
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
NCI-H460 IC50
38.49 μM
Compound: 4
Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell proliferation by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as inhibition of cell proliferation by MTT assay
[PMID: 33609662]
In Vitro

6-Prenylapigenin (compound 2) shows cytotoxicity on different cancer cell lines with IC50 values of 1.7 μM, 11.2 μM, and 13.8 μM on MCF-7, PF-382, and Caski cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Prenylapigenin Related Antibodies
Molecular Weight

338.35

Formula

C20H18O5
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

OC1=C2C(OC(C3=CC=C(O)C=C3)=CC2=O)=CC(O)=C1C/C=C(C)/C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 98.0%

SDS (252 KB)

COA (246 KB)

Handling Instructions (2659 KB)
References
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6-Prenylapigenin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Prenylapigenin68097-13-26-Prenyl-4',5,7-trihydroxyflavone 6-C-PrenylapigeninOtherscolumn chromatographyprenylated flavonoidchloroform extractsMaclura pomiferastemsleavesInhibitorinhibitorinhibit

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