1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Sfllrnpndkyepf

Sfllrnpndkyepf 

Cat. No.: HY-P1000 Purity: 98.22%
Handling Instructions

SFLLRNPNDKYEPF is a synthetic thrombin receptor agonist peptide.

For research use only. We do not sell to patients.

Sfllrnpndkyepf Chemical Structure

Sfllrnpndkyepf Chemical Structure

CAS No. : 137339-65-2

Size Price Stock Quantity
10 mM * 1 mL in Water USD 1470 In-stock
Estimated Time of Arrival: December 31
1 mg USD 108 In-stock
Estimated Time of Arrival: December 31
5 mg USD 432 In-stock
Estimated Time of Arrival: December 31
10 mg USD 768 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

SFLLRNPNDKYEPF is a synthetic thrombin receptor agonist peptide.

In Vitro

Thrombin cleaves its receptor at arginine-41, resulting in the generation of a new receptor NH2-terminus with the sequence SFLLRNPNDKYEPF. This peptide (TRP-14) may signal a variety of thrombin's responses[1]. SFLLRNPNDKYEPF, representing the 14 amino acids starting with Ser-42 of the human thrombin receptor, was found to mimic the effect of thrombin on platelets. Cleavage of the human platelet thrombin receptor by thrombin exposes a new N-terminal which acts as a putative tethered ligand. SFLLRNPNDKYEPF, corresponding to the new N-terminal region, activates and induces platelet aggregation and serotonin secretion. SFLLRNPNDKYEPF is the minimal peptide length which retains full activity in inducing [14C]serotonin secretion[2]. TRAP induces rapid morphological changes in HUVECs, with marked increase in the release of prostacyclin, endothelin, platelet activating factor, tissue type plasminogen activator, and plasminogen activator inhibitor-1. Incubation of cells with TRAP also induces a rapid decrease in cell-surface thrombomodulin[3].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

1739.92

Formula

C₈₁H₁₁₈N₂₀O₂₃

CAS No.

137339-65-2

SMILES

[SFLLRNPNDKYEPF]

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Sfllrnpndkyepf
Cat. No.:
HY-P1000
Quantity:

Sfllrnpndkyepf

Cat. No.: HY-P1000