2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Amine N-methyltransferase

Amine N-methyltransferase

Amine N-methyltransferase

Amine N-methyltransferase is an enzyme that catalyzes the N-methylation reaction of amine compounds. According to the substrates of Amine N-methyltransferase, it can be classified into PNMT, NNMT, GNMT and HNMT. Amine N-methyltransferase is involved in physiological processes such as neurotransmitter metabolism and bioactive natural products synthesis. Changes in the activity of amine Amine N-methyltransferase are related to the occurrence and development of diseases such as neurological diseases and cancers[1].

Amine N-methyltransferase Isoform Specific Products:

Amine N-methyltransferase Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W1006754
    NNMT-IN-7
    		Inhibitor 98.0%
    NNMT-IN-7 (Compound 4e) is a NNMT inhibitor (IC50 = 505.7 µM). NNMT-IN-7 can be used in studies of metabolic and chronic diseases.
    NNMT-IN-7
  • HY-107398R
    1-(2,3-Dichlorophenyl)ethanamine hydrochloride (Standard)
    		Inhibitor
    1-(2,3-Dichlorophenyl)ethanamine hydrochloride (Standard) is the analytical standard of 1-(2,3-Dichlorophenyl)ethanamine (hydrochloride) (HY-107398). This product is intended for research and analytical applications. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure.
    1-(2,3-Dichlorophenyl)ethanamine hydrochloride (Standard)
Amine N-methyltransferase Isoform Comparison

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