2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Amine N-methyltransferase
  5. PNMT Isoform

PNMT

 

PNMT Related Products (1):

Cat. No. Product Name Effect Purity
  • HY-142110
    LY 78335
    		Inhibitor
    LY 78335 (DCMB) is a brain-penetrant phenylethanolamine-N-methyltransferase (PNMT) inhibitor with a Ki of 0.09 μM. LY 78335 acts as an α₂-adrenoceptor inhibitor with an IC50 of 10 μM. LY 78335 increases spontaneous locomotor activity in rats. LY 78335 increases extracellular concentration of 3-methoxy-4-hydroxyphenylglycol (MHPG) in rat hypothalamus. LY 78335 prevents growth hormone (GH) secretion in rats. LY 78335 can be used for the research of depression.