Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1734):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W014553

N-Acetyl-D-phenylalanine		99.81%
N-Acetyl-D-phenylalanine is a phenylalanine derivative.

HY-W008446

(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid		99.80%
(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative.

HY-W038703

(tert-Butoxycarbonyl)-L-valyl-L-alanine		98.0%
(tert-Butoxycarbonyl)-L-valyl-L-alanine is an alanine derivative.

HY-134852

Fmoc-Cys(STmp)-OH		98.93%
Fmoc-Cys(STmp)-OH is a cysteine derivative.

HY-W005143

(S)-2-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid		98.0%
(S)-2-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoic acid is a glutamic acid derivative.

HY-W016012

Glu-Glu		98.0%
Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption.

HY-W016427

H-Leu-OMe.HCl		98.0%
H-Leu-OMe.HCl is a leucine derivative.

HY-W011199

Boc-Tyr(tBu)-OH		99.94%
Boc-Tyr(tBu)-OH is a tyrosine derivative.

HY-W010724

Fmoc-D-Cys(Trt)-OH		99.37%
Fmoc-D-Cys(Trt)-OH is a cysteine derivative.

HY-W048682

Fmoc-1-methyl-L-histidine		99.20%
Fmoc-1-methyl-L-histidine is an Fmoc-protected amino acid as well as an amino acid-containing building block. Fmoc-1-methyl-L-histidine is applicable to the generation of the ε-nitrogen-coordinated copper center in nitrite copper reductase. It also serves as an intermediate in peptide synthesis.

HY-W009258

Boc-Tyr(Me)-OH		99.85%
Boc-Tyr(Me)-OH is a tyrosine derivative.

HY-77026

(S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate		99.88%
(S)-Ethyl 2-amino-4-fluoro-4-methylpentanoate sulfate is a leucine derivative.

HY-W010077

H-Val-OMe.HCl
H-Val-OMe.HCl is a valine derivative.

HY-W141919

N-(2-Methylbutyryl)glycine		99.0%
N-(2-Methylbutyryl)glycine is a Glycine (HY-Y0966) derivative.

HY-W012437

Boc-Thr-OH
Boc-Thr-OH is a threonine derivative.

HY-W001158S

N,N-Dimethylglycine-d₆ hydrochloride		99.46%
N,N-Dimethylglycine-d₆ (Dimethylglycine-d₆) hydrochloride is the deuterium labeled N,N-Dimethylglycine hydrochloride (HY-W001158). N,N-Dimethylglycine (Dimethylglycine) hydrochloride, a natural N-methylated glycine, is a nutrient supplement and acts as an NMDAR glycine site partial agonist. N,N-Dimethylglycine hydrochloride is a methyl donor that can improve immunity, act as an antioxidant to prevent oxidative stress, and scavenge excess free radicals. N,N-Dimethylglycine hydrochloride has antidepressant-like and surfactant effects.

HY-B1258

4-(Aminomethyl)benzoic acid		99.99%
4-(Aminomethyl)benzoic acid is a competitive inhibitor of PepT1 and has antifibrinolytic activity.

HY-W009005

Fmoc-HoPhe-OH		99.71%
Fmoc-HoPhe-OH is a phenylalanine derivative.

HY-W011002

Fmoc-3-Ala(2-thienyl)-OH		99.53%
Fmoc-3-Ala(2-thienyl)-OH is an alanine derivative.

HY-W009562

H-Met-OtBu.HCl		99.69%
H-Met-OtBu.HCl is a Methionine (HY-13694) derivative.

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