2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. ATP-binding cassette (ABC) transporters
  5. Multidrug resistance proteins (MRPs) Isoform
  6. Multidrug resistance proteins (MRPs) Inhibitor

Multidrug resistance proteins (MRPs) Inhibitor

Multidrug resistance proteins (MRPs) Inhibitor (1):

Cat. No. Product Name Effect Purity
  • HY-W010649
    Isoxazole
    		Inhibitor 99.98%
    Isoxazole is a member of the five-membered heterocycle drug scaffold. Isoxazole has been used as a BET bromodomain inhibitor and can improve β-cell function in a diabetic mouse model. Isoxazole and its derivatives exhibit broad biological activities (such as antimicrobial, antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, immunomodulatory, analgesic, anti-tuberculosis, and anti-diabetic effects). For example, the bicyclic Isoxazole can act as an HSP90 inhibitor, and the tricyclic Isoxazole is promising as a selective multidrug resistance protein (MRP1) inhibitor​.