2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W131311
    m-Chlorohippuric acid
    		99.46%
    m-Chlorohippuric acid (3-Chlorohippuric acid) is a substituted hippurate and substrate for peptidylglycine α-hydroxylating monooxygenase (PHM). m-Chlorohippuric acid can be used in research on cancer, rheumatoid arthritis, depression, and pesticides.
    m-Chlorohippuric acid
  • HY-47598
    Analgesic agent-3
    Analgesic agent-3 (compound 3d) is a potent analgesic agent.
    Analgesic agent-3
  • HY-W777361
    11a-Hydroxy Progesterone b-D-Glucuronide
    11a-Hydroxy Progesterone b-D-Glucuronide (11α-Glucuronylprogesterone) is a progesterone derivative.
    11a-Hydroxy Progesterone b-D-Glucuronide
  • HY-123068R
    Captopril disulfide (Standard)
    Captopril disulfide (Standard) is the analytical standard of Captopril disulfide. This product is intended for research and analytical applications. Captopril disulfide is a metabolite of Captopril with antihypertensive activity.
    Captopril disulfide (Standard)
  • HY-164158
    N,N-Dimethyl psychosine
    N,N-Dimethyl psychosine is a derivative of Psychosine (HY-136490). N,N-Dimethyl psychosine can be used as an internal standard compound to quantify Psychosine in alkaline-treated lipid extracts.
    N,N-Dimethyl psychosine
  • HY-135073
    PCMPA hydrochloride
    		Control
    PCMPA hydrochloride a derivative of Phencyclidine that can be metabolized by cytochrome P450 isoenzymes (P450s).
    PCMPA hydrochloride
  • HY-W011053GL
    Neotame (GMP Like)
    Neotame (GMP Like) is the GMP Like class Neotame (HY-W011053) that can be used as pharmaceutical excipients. Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells.
    Neotame (GMP Like)
  • HY-W740240
    trans-9,10-Epoxy-octadecanoic acid
    trans-9,10-Epoxy-octadecanoic acid is an ester product.
    trans-9,10-Epoxy-octadecanoic acid
  • HY-W001026
    2-Benzyloxybenzoic acid
    		99.79%
    2-Benzyloxybenzoic acid is a Benzyloxy-benzene (HY-W022039) derivative.
    2-Benzyloxybenzoic acid
  • HY-175124
    ADB-ICA
    ADB-ICA is a drug derivative that can be used in research on neurological diseases.
    ADB-ICA
  • HY-19187
    Acyclovir elaidate
    Acyclovir elaidate (P-4010) is an orally active anti-HSV compound and Acyclovir (HY-17422) derivative. Acyclovir elaidate has the effect of ameliorating the symptoms of clinical disease in the experimental female guinea pig model of genital herpes.
    Acyclovir elaidate
  • HY-174293
    Osimertinib dimer
    Osimertinib dimer is a dimer of Osimertinib (HY-15772). Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.
    Osimertinib dimer
  • HY-172061
    3,4-EDMC hydrochloride
    3,4-EDMC hydrochloride is a drug derivative.
    3,4-EDMC hydrochloride
  • HY-138095
    ALEPH-4
    ALEPH-4 is an analog of 2,5-Dimethoxy-4-isopropylthiophenethylamine.
    ALEPH-4
  • HY-119844A
    Anidoxime hydrochloride
    		Inhibitor
    Anidoxime hydrochloride is an Amidoxime derivative, and an orally active analgesic agent. Anidoxime hydrochloride can be used for the research of post-surgical pain.
    Anidoxime hydrochloride
  • HY-N15387
    Hericenone J
    Hericenone J (Compound 6) is an aromatic compound with anticancer activity, which is found in Hericium erinaceum. Hericenone J is cytotoxic and can significantly reduce the viability of HL-60 human acute promyelocytic leukemia cells with an IC50 value of 4.13 μM. Hericenone J is promising for research of leukemia.
    Hericenone J
  • HY-106304
    ME-1228
    ME-1228 is an antibacterial agent and sulfur-containing analogue of OCP 9-176. ME 1228 is generally twofold more active than OCP 9-176 against Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Providencia stuartii, Proteus vulgaris, and Serratia marcescens. ME-1228 has antibacterial activity against E. coli UB 1005, P. aeruginosa K779K, and P. aeruginosa E4, with MICs of 0.25, 0.25, and 1 μg/mL, respectively.
    ME-1228
  • HY-108409R
    Progesterone carboxylic acid (Standard)
    Progesterone carboxylic acid (Standard) is the analytical standard of Progesterone carboxylic acid (HY-108409). This product is intended for research and analytical applications. Progesterone carboxylic acid (Testosterone-17β-carboxylic acid) is an androstenedione analogue. Progesterone carboxylic acid can conjugate with 20-mer peptide nucleic acid (PNA) and the conjugate has superior binding capacity on complementary DNA. Progesterone carboxylic acid can be used for cancers and type 2 diabetes (T2D) research.
    Progesterone carboxylic acid (Standard)
  • HY-W106785
    N-Benzylcyclohexylamine hydrochloride
    		Control
    N-Benzylcyclohexylamine hydrochloride, an arylcyclohexylamine, is a cutting agent in 3,4-MDMA samples.
    N-Benzylcyclohexylamine hydrochloride
  • HY-W350447
    7,8-DimeIQX
    7,8-DimeIQX is a mutagenic/carcinogenic heterocyclic aromatic amine.
    7,8-DimeIQX