2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N17541
    Aurantinidin chloride
    Aurantinidin (chloride) is a natural product that can be found in impatiens.
    Aurantinidin chloride
  • HY-N16777
    Pruniflorone R
    Pruniflorone R is a natural xanthone.
    Pruniflorone R
  • HY-N13779
    Trigonothyrin D
    Trigonothyrin D is a natural diterpene.
    Trigonothyrin D
  • HY-113455S1
    9(S)-HODE-13C18
    9(S)-HODE-13C18 ((+)-α-Dimophecolic acid-13C18) is 13C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO.
    9(S)-HODE-<sup>13</sup>C<sub>18</sub>
  • HY-N15846
    VSA 1
    VSA 1, a semisynthetic QS-21 (HY-101092) analog, is a saponin adjuvant. VSA 1 potentiates antigen-specific IgG1 and IgG2a immune responses in BALB/c mice, indicating a mixed Th1/Th2 immune response. VSA 1 significantly improves vaccine efficacy after primary immunization and enhances homologous protection.
    VSA 1
  • HY-126555
    OX3a
    OX3a is an active compound.
    OX3a
  • HY-106516
    Napactadine free base
    Napactadine (free base) (compound 33) has anti-depressive activity. Napactadine has oral activity.
    Napactadine free base
  • HY-133600
    4,5,6-Trichloroguaiacol
    4,5,6-Trichloroguaiacol is a phenolic compound occurring in effluents from bleached kraft pulp mills.
    4,5,6-Trichloroguaiacol
  • HY-N9841
    Scolopianate A
    Scolopianate A is a natural triterpene.
    Scolopianate A
  • HY-N16407
    Austdiol
    Austdiol (NSC 159632) is an azaphilone derivative with antimicrobial activity. Austdiol is promising for research of infectious diseases.
    Austdiol
  • HY-N17560
    3β-Acetoxy-(20S,22E)-dammaran-22-en-25-ol
    3β-Acetoxy-(20S,22E)-dammaran-22-en-25-ol is a natural product that can be found in frankincense.
    3β-Acetoxy-(20S,22E)-dammaran-22-en-25-ol
  • HY-N17033
    1α,7α,10αH-Guaian-4,11-dien-3-one
    1α,7α,10αH-Guaian-4,11-dien-3-one is a natural sesquiterpene.
    1α,7α,10αH-Guaian-4,11-dien-3-one
  • HY-N19886
    Pastuchoside E
    Pastuchoside E is a triterpenoid saponin found in the leaves of Hedera pastuchowii. Terpenes, also known as isoprene compounds, are the most numerous and structurally diverse natural products found in many plants. Terpenes can be used to treat cancer, malaria, inflammation, and various infectious diseases.
    Pastuchoside E
  • HY-N16696
    Escin IVf
    Escin IVf is a natural triterpene.
    Escin IVf
  • HY-122176
    NU-7107
    NU-7107 is a derivative of NU7026 (HY-15719) and a DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 >10 μM. NU-7107 is applicable for cancer research.
    NU-7107
  • HY-N9845
    Thymyl 2-methylvalerate
    Thymyl 2-methylvalerate is a natural terpenoid.
    Thymyl 2-methylvalerate
  • HY-W740576
    7-Descarbamoyl-17-amino geldanamycin
    7-Descarbamoyl-17-amino geldanamycin is a Geldanamycin (HY-15230) derivative. 7-Descarbamoyl-17-amino geldanamycin exerts very low activity in depleting p185erbB-2 protein in human breast cancer cells in vitro.
    7-Descarbamoyl-17-amino geldanamycin
  • HY-N2796
    9β-Hydroxydarutigenol
    9β-Hydroxydarutigenol is a natural diterpene.
    9β-Hydroxydarutigenol
  • HY-168421
    3',4'-Dimethyl-α-ethylaminovalerophenone hydrochloride
    3',4'-Dimethyl-α-ethylaminovalerophenone hydrochloride is a drug derivative.
    3',4'-Dimethyl-α-ethylaminovalerophenone hydrochloride
  • HY-N17144
    Procumboside A
    Procumboside A is a natural phenolic compound.
    Procumboside A