2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W708163
    4-Desacetamido-4-chloro andarine-d4
    4-Desacetamido-4-chloro andarine-d4 is the deuterium labeled (S)-3-(4-Chlorophenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide (HY-W708162).
    4-Desacetamido-4-chloro andarine-d<sub>4</sub>
  • HY-Y1055S2
    Guanine-13C5,15N5
    Guanine-13C5,15N5 is 13C and 15N-labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects.
    Guanine-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N<sub>5</sub>
  • HY-W015339S2
    Octanoate-d15 sodium
    Octanoate-d15 (sodium) is the deuterium labeled Octanoate.
    Octanoate-d<sub>15</sub> sodium
  • HY-W777535
    Naphthalene-13C10
    Naphthalene-13C10 is 13C labeled Naphthalene-13C10 (HY-W777535).
    Naphthalene-<sup>13</sup>C<sub>10</sub>
  • HY-W778649
    Sarmentine-d8
    Sarmentine-d8 is the deuterium labeled Sarmentine. Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC50 of 3.0 μM and a Ki of 1.5 μM against spinach, an IC50 of 1.72 μM against wild-type Amaranthus retroflexus, and an IC50 of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the QB binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC50 of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities.
    Sarmentine-d<sub>8</sub>
  • HY-W742819
    3-O-Benzyl Estradiol-d3
    3-O-Benzyl Estradiol-d3 is the deuterium labeled 3-O-Benzyl Estradiol (HY-W740878).
    3-O-Benzyl Estradiol-d<sub>3</sub>
  • HY-143988S
    Nefazodone impurity 3-d6
    Nefazodone impurity 3-d6 is the deuterium labeled Nefazodone impurity 3.
    Nefazodone impurity 3-d<sub>6</sub>
  • HY-Y0400S
    2-Bromoethylammonium-d4 bromide
    2-Bromoethylammonium-d4 bromide is the deuterium labeled 2-Bromoethylammonium bromide[1].
    2-Bromoethylammonium-d<sub>4</sub> bromide
  • HY-W008507S3
    (R)-2,3-Dihydroxypropanal-d
    (R)-2,3-Dihydroxypropanal-d is the deuterium labeled (R)-2,3-Dihydroxypropanal.
    (R)-2,3-Dihydroxypropanal-d
  • HY-Y0921S1
    (±)-1,2-Propanediol-d2
    (±)-1,2-Propanediol-d2 is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents.
    (±)-1,2-Propanediol-d<sub>2</sub>
  • HY-172439S
    Simedeutirom
    Simedeutirom is the agonist for thyroid hormone beta receptor (THRβ) and can be used for researchs of metabolic diseases, such as obesity and diabetes mellitus.
    Simedeutirom
  • HY-142547S
    S 421-d4
    S 421-d4 is the deuterium labeled S 421.
    S 421-d<sub>4</sub>
  • HY-144148S
    Pyroxsulam-13C,d3
    Pyroxsulam-13C,d3 is the 13C- and deuterium labeled Pyroxsulam.
    Pyroxsulam-<sup>13</sup>C,d<sub>3</sub>
  • HY-113404S
    DL-Dopa-d6
    DL-Dopa-d6 is the deuterium labeled DL-Dopa. DL-Dopa is a beta-hydroxylated derivative of phenylalanine.
    DL-Dopa-d<sub>6</sub>
  • HY-W777545
    4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol-d4
    4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol-d4 is the deuterium labeled Hydroxychloroquine Impurity E (HY-131262). Hydroxychloroquine Impurity E is the impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro.
    4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol-d<sub>4</sub>
  • HY-B0916S
    Propoxur-d3
    Propoxur-d3 is the deuterated form of Propoxur (HY-B0916). Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests.
    Propoxur-d<sub>3</sub>
  • HY-167855S
    1’-Epi Gemcitabine hydrochloride-13C,15N2
    1’-Epi Gemcitabine hydrochloride-13C,15N2 is the 13C- and 15N-labeled MRS4833 (HY-167855). MRS4833 (compound 15) is an orally active, potent, competitive P2Y14R antagonist with an of IC50 of 5.92 nM for hP2Y14R and an IC50 of 4.8 nM for mP2Y14R. MRS4833 reduces airway eosinophilia in a protease-mediated asthma model and reverses chronic neuropathic pain in a mouse CCI model.
    1’-Epi Gemcitabine hydrochloride-<sup>13</sup>C,<sup>15</sup>N<sub>2</sub>
  • HY-143839S
    N-Ethyl-N-nitroso-1-propanamine-d4
    N-Ethyl-N-nitroso-1-propanamine-d4 is the deuterium labeled N-Ethyl-N-nitroso-1-propanamine.
    N-Ethyl-N-nitroso-1-propanamine-d<sub>4</sub>
  • HY-W699933
    4-(2-Aminoethoxy)-3-methoxyphenol-d3
    4-(2-Aminoethoxy)-3-methoxyphenol-d3 is the deuterium labeled 4-(2-Aminoethoxy)-3-methoxyphenol (HY-W239958).
    4-(2-Aminoethoxy)-3-methoxyphenol-d<sub>3</sub>
  • HY-135389S
    Desmethyl Levofloxacin-d8 hydrochloride
    Desmethyl Levofloxacin-d8 hydrochloride is the deuterium labeled Desmethyl Levofloxacin. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
    Desmethyl Levofloxacin-d<sub>8</sub> hydrochloride