Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-P0073S

Tyr-Gly-Gly-{Phe-¹³C₉,¹⁵N}-Met-OH TFA
Tyr-Gly-Gly-{Phe-¹³C₉,¹⁵N}-Met-OH TFA (Met-Enkephalin-¹³C₉,¹⁵N TFA) is the ¹³C- and ¹⁵N-labeled Tyr-Gly-Gly-Phe-Met-OH TFA. Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

HY-B0007S2

Baclofen-d₅ hydrochloride
Baclofen-d₅ hydrochloride is deuterated labeled Baclofen (HY-B0007). Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABA_B receptor (GABA_BR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABA_B receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research.

HY-132390S

Normesuximide-d₅
Normesuximide-d₅ is the deuterium labeled Normesuximide.

HY-10450S3

Dapagliflozin-¹³C₆
Dapagliflozin-¹³C₆ (BMS-512148-¹³C₆) is ¹³C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine. Dapagliflozin induces HIF1 expression and attenuates renal IR injury.

HY-B0503S

2-Thiouracil-¹³C,¹⁵N₂
2-Thiouracil-¹³C,¹⁵N₂ is the ¹³C, ¹⁵N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM.

HY-W011026S1

Fmoc-D-Phe-OH-d₈
Fmoc-D-Phe-OH-d₈ is the deuterium labeled Fmoc-D-Phe-OH.

HY-W011240S1

Hydroflumethiazide-¹⁵N₂,¹³C,d₂
Hydroflumethiazide-¹⁵N₂,¹³C,d₂ is the ¹³C- and ¹⁵N-labeled Hydroflumethiazide.

HY-B1912S

Amidosulfuron-d₆
Amidosulfuron-d₆ is deuterium labeled Amidosulfuron.

HY-W702217

4-Ethylpyridine-2-carbonitrile-d₅
4-Ethylpyridine-2-carbonitrile-d₅ (4-Ethyl-2-pyridinecarbonitrile-d₅) is the deuterium labeled 4-Ethylpyridine-2-carbonitrile (HY-W176013).

HY-N0379S17

D-Mannose-d-3
D-Mannose-d-3 is the deuterium labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote.

HY-W704589

2-(Carbamoylamino)pentanedioic acid-d₅
2-(Carbamoylamino)pentanedioic acid-d₅ (N-carbamoylglutamic acid-d₅) is the deuterium labeled 2-(Carbamoylamino)pentanedioic acid (HY-W169233).

HY-178087S

Butane-d₆
Butane-d₆ is the deuterium labeled Butene, homopolymer.

HY-12767S

4-Hydroxyphenyl Carvedilol-d₅
4-Hydroxyphenyl Carvedilol-d₅ is the deuterium labeled 4-Hydroxyphenyl Carvedilol.

HY-W004113S

3,5-Dichlorophenol-d₃
3,5-Dichlorophenol-d₃ is the deuterium labeled 3,5-Dichlorophenol.

HY-W220946S

2-Chlorobutanoic acid-d₆		98.4%
2-Chlorobutanoic acid-d₆ is the deuterium labeled 2-Chlorobutanoic acid.

HY-13604S1

Cyproterone acetate-d₆
Cyproterone acetate-d₆ is the deuterium labeled Cyproterone acetate (HY-13604). Cyproterone acetate is an anti-androgen (IC₅₀=7.1 nM) and progestogen synthetic steroid. Cyproterone acetate has affinity with progesteron and with glucocorticoidal receptors.

HY-N0113BS

Hordenine-d₆ hydrochloride
Hordenine-d₆ (Ordenina-d₆; Peyocactine-d₆) hydrochloride is deuterium-labeled Hordenine (hydrochloride) (HY-N0113B).

HY-W012478S

6-Phenyl-2-thiouracil-¹³C,¹⁵N₂
6-Phenyl-2-thiouracil-¹³C,¹⁵N₂ is the ¹³C, ¹⁵N labeled 6-Phenyl-2-thiouracil.

HY-13862S

AZD1080-d₈
AZD1080-d₈ is the deuterium labeled AZD1080 (HY-13862). AZD1080 is a potent and selective GSK3 inhibitor. AZD1080 inhibits recombinant human GSK3α and GSK3β with pK_i (IC₅₀) of 8.2 (6.9 nM) and 7.5 (31 nM), respectively.

HY-100642S

3-O-Methyltolcapone-d₇		99.0%
3-O-Methyltolcapone-d₇ (Ro 40-7591 d₇) is a deuterium labeled 3-O-Methyltolcapone (HY-174062). 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC₅₀of 773 nM. Tolcapone can inhibits α-syn and Aβ₄₂ oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.

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