1. Metabolic Enzyme/Protease
    Neuronal Signaling
  2. COMT
  3. 3-O-Methyltolcapone D7

3-O-Methyltolcapone D7 (Synonyms: Ro 40-7591 D7)

Cat. No.: HY-100642S
Handling Instructions

3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease.

For research use only. We do not sell to patients.

3-O-Methyltolcapone D7 Chemical Structure

3-O-Methyltolcapone D7 Chemical Structure

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Description

3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease[1][2].

IC50 & Target

COMT[1][2]

Molecular Weight

294.31

Formula

C₁₅H₆D₇NO₅

SMILES

OC(C(OC)=C1)=C(C=C1C(C2=C([2H])C([2H])=C(C([2H])=C2[2H])C([2H])([2H])[2H])=O)[N+]([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

3-O-Methyltolcapone D7Ro 40-7591 D7COMTCatechol-O-methyltransferaseMetabolitedeuteriumlabeledTolcaponeblood-brainbarrierParkinson'sdiseaseInhibitorinhibitorinhibit

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3-O-Methyltolcapone D7
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