SGLT2

SGLT2 Related Products (21):

By Type:	Pan (2) Selective (5)

Cat. No.	Product Name	Effect	Purity

HY-10450

Dapagliflozin	Inhibitor	99.87%
Dapagliflozin (BMS-512148), a new type of drug used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine.

HY-N0142

Phloretin	Inhibitor	99.67%
Phloretin (NSC 407292; RJC 02792) is a flavonoid extracted from Malus pumila Mill.

HY-N0143

Phlorizin	Inhibitor	99.82%
Phlorizin is a non-selective SGLT inhibitor with K_is of 300 and 39 nM for hSGLT1 and hSGLT2, respectively.

HY-15461

Ertugliflozin	Inhibitor	99.85%
Ertugliflozin (PF-04971729) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC₅₀ of 0.877 nM for h-SGLT2.

HY-14894

Ipragliflozin	Inhibitor	99.78%
Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC₅₀s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively.

HY-10449

Luseogliflozin	Inhibitor
Luseogliflozin (TS 071) is a potent, selective, orally active sodium-dependent glucose cotransporter (SGLT) 2 inhibitor, with an IC₅₀ of 2.26 nM, about 1765-fold selectivity over SGLT1 (IC₅₀, 3990 nM).

HY-12611

Sergliflozin etabonate	Inhibitor
Sergliflozin etabonate (GW-869682X) is a potent and orally active sodium glucose cotransporter (SGLT2) inhibitor.

HY-109018B

Velagliflozin proline hydrate	Inhibitor
Velagliflozin proline hydrate is the clinical form of Velagliflozin (HY-109018).

HY-10450A

Dapagliflozin ((2S)-1,2-propanediol, hydrate)	Inhibitor	99.99%
Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate.

HY-N4100

Trilobatin	Inhibitor	98.85%
Trilobatin, a natural sweetener derived from Lithocarpus polystachyus Rehd, Trilobatin is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope.

HY-14945

Remogliflozin etabonate	Inhibitor	99.64%
Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity sodium glucose cotransporter (SGLT2) inhibitor with K_i values of 1.95 μM, 2.14 μM, 43.1 μM, 8.57 μM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively.

HY-15461A

Ertugliflozin L-pyroglutamic acid	Inhibitor	99.77%
Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC₅₀ of 0.877 nM for h-SGLT2.

HY-109018

Velagliflozin	Inhibitor	99.92%
Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.

HY-10450S

Dapagliflozin-d₅	Inhibitor	98.08%
Dapagliflozin D5 (BMS-512148 D5) is a deuterium labeled Dapagliflozin.

HY-138944

SGLT1/2-IN-1	Inhibitor
SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor extract from WO2015032272A1, compound 2 .

HY-109144

Enavogliflozin	Inhibitor	98.01%
Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor.

HY-10449A

Luseogliflozin hydrate	Inhibitor
Luseogliflozin (TS 071) hydrate is a selective potent and orally active second-generation sodium-glucose co-transporter 2 (SGLT2) inhibitor with an IC₅₀ of 2.26 nM.

HY-117010

Kushenol K	Inhibitor
Kushenol K, a flavonoid antioxidant isolated from the roots of Sophora flavescens.

HY-106158

T-1095	Inhibitor
T-1095 is a selective and orally active Na⁺-glucose cotransporter (SGLT) inhibitor with IC₅₀s of 22.8 µM and 2.3 µM for human SGLT1 and SGLT2, respectively.

HY-12608

TA-1887	Inhibitor
TA-1887 (JNJ-39933673) is a highly potent, selective and orally active SGLT2 inhibitor (IC₅₀: 1.4 nM) with antihyperglycemic effects.

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