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Cat. No.: HY-I1198

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Dapagliflozin keto impurity

Name: Dapagliflozin keto impurity
Brand: MedChemExpress
SKU: HY-I1198
Price: 40.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Oxo-dapagliflozin)

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Dapagliflozin keto impurity (Oxo-dapagliflozin) is an oxo metabolite and related impurity of Dapagliflozin (HY-10450). Dapagliflozin keto impurity can be characterized by ¹H NMR, ¹³C NMR and HRMS, and can be used in studies related to Dapagliflozin impurities and metabolites.

For research use only. We do not sell to patients.

Purity: 98.19%
CAS No.: 2169998-23-4
Formula: C₂₁H₂₃ClO₇
Molecular Weight:422.86

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Dapagliflozin keto impurity Chemical Structure

CAS No.: 2169998-23-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

In Vitro

Dapagliflozin keto impurity (Oxo-dapagliflozin) is an off-white amorphous solid, which is prepared via multi-step chemical synthesis using methoxyoxo-dapagliflozin as the starting material with a yield of 80%. Its structure is confirmed by NMR and HRMS^[1].
Dapagliflozin keto impurity is obtained by hydrolyzing tetraacetyl oxo dapagliflozin with LiOH·H₂O. The reaction proceeds at 20-30°C for 16 h, with a yield of 84%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2169998-23-4
Appearance Solid
Molecular Weight 422.86
Formula C₂₁H₂₃ClO₇
Color White to off-white
SMILES

ClC1=CC=C([C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C=C1C(C3=CC=C(OCC)C=C3)=O
Synonyms

Oxo-dapagliflozin
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (286 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Karumanchi K, et al. Synthesis of metabolites of dapagliflozin: an SGLT2 inhibitor. J Chem Sci. 2020;132:42.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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