842133-18-0
842133-18-0
Chemical Structure
Canagliflozin
Synonym(s): JNJ 28431754
- CAS No.: 842133-18-0
- Formula:C24H25FO5S
- Molecular Weight:444.52
IUPAC Name: (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: XTNGUQKDFGDXSJ-ZXGKGEBGSA-N
SMILES: FC1=CC=C(C2=CC=C(CC3=C(C=CC([C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C3)C)S2)C=C1
Biological Activity: Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Canagliflozin | 99.99% | Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively. | ||||||||||||||||||||
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Canagliflozin (Standard) | 99.89% | Canagliflozin (Standard) is the analytical standard of Canagliflozin. This product is intended for research and analytical applications. Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively. | ||||||||||||||||||||
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Canagliflozin-d6 | Canagliflozin-d6 is the deuterium labeled Canagliflozin. Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively. | |||||||||||||||||||||
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Canagliflozin-d4 | 99.04% | Canagliflozin-d4 (JNJ 28431754-d4) is a deuterium labeled Canagliflozin. Canagliflozin is a selective SGLT2 inhibitor. | ||||||||||||||||||||
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References
