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Cat. No.: HY-10451S

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Canagliflozin-d₄

(Synonyms: JNJ 28431754-d₄)

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Based on 1 Customer Validation

Canagliflozin-d₄ (JNJ 28431754-d₄) is a deuterium labeled Canagliflozin. Canagliflozin is a selective SGLT2 inhibitor.

For research use only. We do not sell to patients.

Purity: 99.04%
CAS No.: 1997338-61-0
Formula: C₂₄H₂₁D₄FO₅S
Molecular Weight:448.54

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Canagliflozin-d₄ Chemical Structure

CAS No.: 1997338-61-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Canagliflozin-d₄ (JNJ 28431754-d₄) is a deuterium labeled Canagliflozin. Canagliflozin is a selective SGLT2 inhibitor^[1].

IC₅₀ & Target

SGLT2

All SGLT Isoforms :

SGLT1
SGLT2

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1997338-61-0
Unlabeled Cas 842133-18-0
Appearance Solid
Molecular Weight 448.54
Formula C₂₄H₂₁D₄FO₅S
Color Light yellow to light brown
SMILES

FC1=C([2H])C([2H])=C(C2=CC=C(CC3=C(C=CC([C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)=C3)C)S2)C([2H])=C1[2H]
Synonyms

JNJ 28431754-d₄
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liang Y, et al. Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models. PLoS One. 2012;7(2):e30555. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
- Application
Chemical Information
Purity & Documentation
References

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Canagliflozin-d4

All SGLT Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Canagliflozin-d4 Related Classifications

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Canagliflozin-d₄

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