SGLT Inhibitors

SGLT1

SGLT2

SGLT Inhibitors

Product Name	SGLT1	SGLT2	Purity
Empagliflozin		SGLT2	99.90%
Dapagliflozin		SGLT2	99.95%
Canagliflozin		SGLT2	99.99%
Phloretin	SGLT1	SGLT2	99.92%
Sotagliflozin	SGLT1	SGLT2	99.94%
Bexagliflozin	hSGLT1, IC₅₀: 5.6 μM	hSGLT2, IC₅₀: 2 nM	99.31%
Dapagliflozin keto impurity		SGLT2	98.19%
Hypoglycemic agent 4	SGLT1
Phlorizin	SGLT1	SGLT2	99.93%
Ipragliflozin	hSGLT1, IC₅₀: 1876 nM rSGLT1, IC₅₀: 1166 nM mSGLT1, IC₅₀: 1380 nM	hSGLT2, IC₅₀: 7.38 nM rSGLT2, IC₅₀: 6.73 nM mSGLT2, IC₅₀: 5.64 nM	99.71%
Mizagliflozin	SGLT1		99.20%
Canagliflozin hemihydrate		SGLT2	99.95%
Ertugliflozin		SGLT2	99.92%
Trilobatin	SGLT1	SGLT2	98.90%
Dapagliflozin ((2S)-1,2-propanediol, hydrate)		SGLT2	99.99%
Swertisin		SGLT2	99.54%
Empagliflozin (Standard)		SGLT2
SGLT2-IN-1		SGLT2, IC₅₀: 33 nM	99.82%
Henagliflozin		SGLT2	98.05%
Tofogliflozin hydrate		SGLT2	98.38%
Ipragliflozin L-Proline		SGLT2	99.88%
Ertugliflozin L-pyroglutamic acid		SGLT2	99.84%
Luseogliflozin	SGLT1, IC₅₀: 3990 nM	SGLT2, IC₅₀: 2.26 nM	99.33%
Velagliflozin		SGLT2	99.92%
Dapagliflozin impurity		SGLT2	99.63%
Dapagliflozin-d₅		SGLT2	99.04%
Remogliflozin etabonate	hSGLT1, Ki: 43.1 μM rSGLT1, Ki: 8.57 μM	hSGLT2, Ki: 1.95 μM rSGLT2, Ki: 2.14 μM	99.64%
Phlorizin dihydrate	hSGLT1, IC₅₀: 0.04 μM hSGLT1, Ki: 39 nM	hSGLT2, IC₅₀: 0.17 μM hSGLT2, Ki: 0.31 nM	99.51%
Tianagliflozin		SGLT2	99.96%
Canagliflozin-d₄		SGLT2	99.9%
Licogliflozin	SGLT1	SGLT2	98.03%
Enavogliflozin		SGLT2	98.43%
Dapagliflozin (Standard)		SGLT2
Remogliflozin		SGLT2	99.5%
HSK0935		SGLT2
Phloretin (Standard)	SGLT1	SGLT2
Sergliflozin etabonate		SGLT2	99.64%
T-1095	hSGLT1, IC₅₀: 22.8 μM	hSGLT2, IC₅₀: 2.3 μM	99.40%
Ertugliflozin (Standard)		SGLT2
SGLT1/2-IN-1	SGLT1, IC₅₀: 15.72 mM	SGLT2, IC₅₀: 3.67 mM
Dapagliflozin-¹³C₆-1		SGLT2
Luseogliflozin hydrate		SGLT2	99.20%
rel-Licogliflozin	SGLT1	SGLT2
Atigliflozin	hSGLT1, IC₅₀: 8.2 μM	hSGLT2, IC₅₀: 10 nM
WAY-123783		SGLT2
Velagliflozin proline		SGLT2	99.43%
SGLT1/2-IN-8	SGLT1	SGLT2
YM-543		SGLT2
LX2761	hSGLT1, IC₅₀: 2.2 nM mSGLT1, IC₅₀: 3.7 nM rSGLT1, IC₅₀: 5.7 nM SGLT1, IC₅₀: 5.1 nM (dog) SGLT1, IC₅₀: 1.4 nM (monkey)	mSGLT2, IC₅₀: 1.0 nM SGLT2, IC₅₀: 1.8 nM (dog) SGLT2, IC₅₀: 1.1 nM (monkey) hSGLT2, IC₅₀: 2.7 nM rSGLT2, IC₅₀: 1.1 nM
SAR-7226	SGLT1	SGLT2
Pragliflozin-¹³C₆		SGLT2
Velagliflozin proline hydrate		SGLT2	99.43%
Demethyl-LX2761	SGLT1, IC₅₀: < 150 nM
Janagliflozin	SGLT1, IC₅₀: 4.802 μM	SGLT2, IC₅₀: 0.0058 μM
TA-1887	SGLT1, IC₅₀: 230 nM	SGLT2, IC₅₀: 1.4 nM
SGLT2-IN-3		SGLT2
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (Standard)		SGLT2
YM543 free base		SGLT2
Trilobatin (Standard)	SGLT1	SGLT2
SGLT2-IN-5	SGLT1, IC₅₀: 23 nM	SGLT2, IC₅₀: 0.8 nM
Canagliflozin (Standard)		SGLT2
Ipragliflozin (Standard)		SGLT2
SGLT2-IN-6	SGLT1, IC₅₀: 6.7 nM	SGLT2, IC₅₀: 0.8 nM
Phlorizin (Standard)	SGLT1	SGLT2
TP0438836	hSGLT1, IC₅₀: 28 nM	hSGLT2, IC₅₀: 7 nM
Dapagliflozin-d₄		SGLT2
Sergliflozin-A	SGLT1	SGLT2
galacto-Dapagliflozin	hSGLT1, Ki: 25000 nM	hSGLT2, Ki: 25 nM
SGLT2-IN-4		SGLT2
fluoro-Dapagliflozin	hSGLT1, Ki: 330 nM	hSGLT2, Ki: 5.3 nM

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