Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10875):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-101981S5

Uridine 5'-monophosphate-¹⁵N₂ dilithium		98.00%
Uridine 5'-monophosphate-¹⁵N₂ (5'- Uridylic acid-¹⁵N₂) dilithium is ¹⁵N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.

HY-W012507S

2,6-Dichlorobenzoic acid-d₃
2,6-Dichlorobenzoic acid-d₃ is the deuterium labeled 2,6-Dichlorobenzoic acid.

HY-178298S

3-Amino-5-hydroxybenzoic acid-¹⁵N
3-Amino-5-hydroxybenzoic acid-¹⁵N is a ¹⁵N-labeled form of 3-Amino-5-hydroxybenzoic acid.

HY-W010517S

1-Methyl-5-mercapto-1,2,3,4-tetrazole-d₃		99.97%
1-Methyl-5-mercapto-1,2,3,4-tetrazole-d₃ is the deuterium labeled 1-Methyl-1H-tetrazole-5-thiol.

HY-146910S

CER1 (d18:1/26:0/18:1)-d₉		99.0%
CER1 (d18:1/26:0/18:1)-d₉ is deuterium labeled CER1 (d18:1/26:0/18:1).

HY-118411S1

5-Ethynyl-2'-deoxyuridine-¹³C₂
5-Ethynyl-2'-deoxyuridine-¹³C₂ (EdU-¹³C₂) is the ¹³C-labeled 5-Ethynyl-2'-deoxyuridine (HY-118411). 5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation. 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-14558S

Tandospirone-d₈
Tandospirone-d₈ (SM-3997-d₈) is deuterium labeled Tandospirone. Tandospirone (SM-3997) is a potent and selective 5-HT_1A receptor partial agonist, with a K_i of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms.

HY-N0210S12

D-Galactose-¹³C,d
D-Galactose-¹³C,d is the deuterium and ¹³C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.

HY-W152862S

Beta-cypermethrin-d₅
Beta-cypermethrin-d₅ (Alpha-cyano-3-phenoxybenzyl [1R-[1alpha(R*),3beta]]-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate-d₅) is deuterium labeled Beta-cypermethrin.

HY-B0843S

Metalaxyl-¹³C₆		98.4%
Metalaxyl-¹³C₆ is the ¹³C-labeled Metalaxyl. Metalaxyl is a fungicide that inhibits protein synthesis in fungi. Metalaxyl inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s=0.3-3.9 μg/mL).

HY-B1118S3

Secnidazole-d₃
Secnidazole-d₃ (RP-14539-d₃; PM-185184-d₃) is the deuterium labeled Secnidazole (HY-B1118). Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.

HY-163423S

TELAEPTSTR-(Arg-¹³C₆,¹⁵N₄)
TELAEPTSTR-(Arg-¹³C₆,¹⁵N₄) is ¹³C and ¹⁵N labeled TELAEPTSTR-(Arg).

HY-17360S

Tiotropium-d₃ bromide
Tiotropium-d₃ (bromide) is the deuterium labeled Tiotropium (Bromide). Tiotropium bromide (BA-679 BR) is a long-acting anticholinergic bronchodilator. Tiotropium bromide blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide is applicable to research related to chronic obstructive pulmonary disease and asthma.

HY-143826S

O-Desmethyl Mebeverine alcohol-d₅ citrate
O-Desmethyl Mebeverine alcohol-d₅ (citrate) is the deuterium labeled O-Desmethyl Mebeverine alcohol citrate.

HY-132860S

Benzo[e]pyrene-d₁₂		98.9%
Benzo[e]pyrene-d₁₂ is the deuterium labeled Benzo[e]pyrene.

HY-W004691S

4-Methylbenzenesulfonhydrazide-d₃		98.4%
4-Methylbenzenesulfonhydrazide-d₃ is the deuterium labeled 4-Methylbenzenesulfonhydrazide.

HY-B0160S

Lafutidine-d₁₀
Lafutidine-d₁₀ is deuterium labeled Lafutidine. Lafutidine (FRG-8813) is a histamine H2-receptor antagonist (H2RA), with proven gastric mucosal protective effects. Lafutidine can be used for the research of gastroesophageal reflux disease.

HY-W017455S1

2,6-Diethylaniline-¹⁵N
2,6-Diethylaniline-¹⁵N is the deuterium labeled 2,6-Diethylaniline.

HY-P0073S1

Tyr-{Gly-¹³C₂,¹⁵N}-Gly-Phe-Met-OH TFA
Tyr-{Gly-¹³C₂,¹⁵N}-Gly-Phe-Met-OH TFA (Met-Enkephalin-¹³C₂,¹⁵N TFA) is the ¹³C- and ¹⁵N-labeled Tyr-Gly-Gly-Phe-Met-OH TFA. Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

HY-Y1100S1

Cyclopropylmethyl bromide-d₃
Cyclopropylmethyl bromide-d₃ is the deuterium labeled Cyclopropylmethyl bromide (HY-Y1100). Cyclopropylmethyl bromide is an intermediate. Cyclopropylmethyl bromide can be used in the preparation of Firocoxib (HY-14670). Firocoxib (ML 1785713) is a potent, selective, orally active COX-2 inhibitor.

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