2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W738320
    Carboxyphosphamide Benzyl Ester-d4
    Carboxyphosphamide Benzyl Ester-d4 is the deuterium labeled Benzyl 3-((amino(bis(2-chloroethyl)amino)phosphoryl)oxy)propanoate (HY-W701421).
    Carboxyphosphamide Benzyl Ester-d<sub>4</sub>
  • HY-17596S
    Closantel-13C6
    Closantel-13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
    Closantel-<sup>13</sup>C<sub>6</sub>
  • HY-16637S4
    Folic acid-13C5,15N
    Folic acid-15N,13C5 is the 13C5 and 15N labeled Folic acid (HY-16637).
    Folic acid-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N
  • HY-137315S
    TML-6-d3
    TML-6-d3 is the deuterium labeled TML-6. TML-6, an orally active curcumin derivative, inhibits the synthesis of the β-amyloid precursor protein and β-amyloid (Aβ). TML-6 can upregulate Apo E, suppress NF-κB and mTOR, and increase the activity of the anti-
    TML-6-d<sub>3</sub>
  • HY-154787S
    Descarboethoxyloratadine-d6 diacetate
    Descarboethoxyloratadine-d6 diacetate is deuterated labeled Descarboethoxyloratadine.
    Descarboethoxyloratadine-d<sub>6</sub> diacetate
  • HY-122524AS
    7-Methylguanosine-13C,d3 iodide
    7-Methylguanosine-13C,d3 iodide is the 13C- and deuterium labeled 7-Methylguanosine iodide (HY-122524A). 7-Methylguanosine iodide is an iodide of 7-Methylguanosine (HY-122524). 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects.
    7-Methylguanosine-<sup>13</sup>C,d<sub>3</sub> iodide
  • HY-143801S1
    N1, N10-Diacetyl triethylenetetramine-d8
    N1, N10-Diacetyl triethylenetetramine-d8 is the deuterium labeled N1, N10-Diacetyl triethylenetetramine.
    N1, N10-Diacetyl triethylenetetramine-d<sub>8</sub>
  • HY-W741338
    4-(4-Aminophenyl)-3-morpholinone-d4
    4-(4-Aminophenyl)-3-morpholinone-d4 is the deuterium labeled 4-(4-Aminophenyl)morpholin-3-one (HY-50187).
    4-(4-Aminophenyl)-3-morpholinone-d<sub>4</sub>
  • HY-W744223
    (R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d3
    (R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d3 is the deuterium labeled (R)-10-Monohydroxy-10,11-dihydro Carbamazepine (HY-W739854).
    (R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d<sub>3</sub>
  • HY-15407S3
    Sacubitril-13C4
    Sacubitril-13C4 (AHU-377-13C4) is a 13C-labeled version of Sacubitril (HY-15407). Sacubitril is an orally active inhibitor of neprilysin NEP (IC50=5 nM). Sacubitril is used in research on heart failure, hypertension and COVID-19.
    Sacubitril-<sup>13</sup>C<sub>4</sub>
  • HY-W750530
    Sodium 1H,1H,2H,2H-perfluoro hexanesulfonate-13C2
    Sodium 1H,1H,2H,2H-perfluoro hexanesulfonate-13C2 is the 13C-labeled Sodium 1H,1H,2H,2H-perfluoro octanesulfonate.
    Sodium 1H,1H,2H,2H-perfluoro hexanesulfonate-<sup>13</sup>C<sub>2</sub>
  • HY-N0059AS1
    L-(+)-Lyxose-13C-1
    L-(+)-Lyxose-13C-1 is the 13C labeled L-Lyxose.
    L-(+)-Lyxose-<sup>13</sup>C-1
  • HY-N0667S4
    L-Asparagine-4-13C monohydrate
    L-Asparagine-4-13C monohydrate is the 13C-labeled L-Asparagine monohydrate (HY-W017443).L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine-4-<sup>13</sup>C monohydrate
  • HY-B0801S3
    Fexofenadine-d10
    Fexofenadine-d10 is deuterium labeled Fexofenadine.
    Fexofenadine-d<sub>10</sub>
  • HY-14407AS
    Fosaprepitant-d4 dimeglumine
    Fosaprepitant-d4 (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).
    Fosaprepitant-d<sub>4</sub> dimeglumine
  • HY-B1277AS
    Trihexyphenidyl-d5
    Trihexyphenidyl-d5 is deuterium labeled Trihexyphenidyl (HY-B1277A). Trihexyphenidyl is a selective and orally active M1 muscarinic receptor antagonist with an IC50 of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl can be used for the research of Parkinson's disease..
    Trihexyphenidyl-d<sub>5</sub>
  • HY-W423530S
    Bis(2-propylheptyl) phthalate-d4
    Bis(2-propylheptyl) phthalate-d4 (Phthalic acid bis(2-propylheptyl) ester-d4) is a deuterium labeled compound.
    Bis(2-propylheptyl) phthalate-d<sub>4</sub>
  • HY-17502S
    Simvastatin-d11
    Simvastatin-d11 is the deuterium labeled Simvastatin. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
    Simvastatin-d<sub>11</sub>
  • HY-W042357S
    Ac-rC Phosphoramidite-15N
    Ac-rC Phosphoramidite-15N is 15N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
    Ac-rC Phosphoramidite-<sup>15</sup>N
  • HY-Y0124S
    NSC 16590-d6
    		99.72%
    NSC 16590-d6 is the deuterium labeled NSC 16590. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.
    NSC 16590-d<sub>6</sub>