Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11097)
Related Products (11097)
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Creosol-d4
0 ImagesCat. No.: HY-W040971SCAS No.: 20189-08-6Synonyms: 2-Methoxy-4-methylphenol-d4Creosol-d4 (2-Methoxy-4-methylphenol-d4) is the deuterium labeled Creosol (HY-W040971). Creosol (2-Methoxy-4-methylphenol) is an endogenous metabolite that acts as an important chemical intermediate and potential biofuel mainly derived from lignocellulosic biomass. Creosol is blood brain barrier penetrable.
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9-cis-Retinol acetate-d5
0 ImagesCat. No.: HY-16760SCAS No.: 1217219-62-9Synonyms: 9-cis-Vitamin A acetate-d5; Zuretinol acetate-d59-cis-Retinol acetate-d5 is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative.
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Guanine-d5
0 ImagesCat. No.: HY-Y1055S6Guanine-d5 is the deuterium labeled Guanine (HY-Y1055). Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool. Guanine has cytotoxic, antinociceptive and neuroprotective effects.
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[U-13C,15N]-Aβ(1-42)
![[U-13C,15N]-Aβ(1-42)](https://file.medchemexpress.com/product_pic/hy-187249s.gif "Click to View [U-13C,15N]-Aβ(1-42) Product Detail")
0 ImagesCat. No.: HY-187249S[U-13C,15N]-Aβ(1-42) is the 13C- and 15N-labeled Aβ(1-42). Abnormal levels and aggregation of beta-amyloid (Aβ) in the brain are considered key factors in the pathogenesis of Alzheimer's disease (AD). This isotope can be used in NMR studies of disease mechanisms and in mass spectrometry analysis.
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D-Ribose-d
0 ImagesCat. No.: HY-W018772S6CAS No.: 119540-50-0D-Ribose-d is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein gly
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N-Nitrosocytisine-d4
0 ImagesCat. No.: HY-W744115CAS No.: 2714437-79-1N-Nitrosocytisine-d4 is the deuterium labeled N-Nitrosocytisine.
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Azelaic acid 2-ethylhexyl monoester-d14
0 ImagesCat. No.: HY-143910SAzelaic acid 2-ethylhexyl monoester-d14 is the deuterium labeled Azelaic acid 2-ethylhexyl monoester.
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Emedastine-13C,d3 fumarate
0 ImagesCat. No.: HY-108411SCAS No.: 2934886-28-7Emedastine-13C,d3 fumarate is the 13C- and deuterium labeled Emedastine. Emedastine is an orally active, selective and high affinity histamine H1 receptor antagonist with a Ki value of 1.3 nM. Emedastine is a benzimidazole derivative with potent antiallergic properties and used for allergic rhinitis, allergic skin diseases and allergic conjunctivitis.
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D-Alanine-3,3,3-N-t-Boc-d3
0 ImagesD-Alanine-3,3,3-N-t-Boc-d3 is the deuterium labeled D-Alanine-3,3,3-N-t-Boc.
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3-Hydroxy tibolone-d5 (mixture of 3a & 3b isomers)
0 ImagesCat. No.: HY-W7442153-Hydroxy tibolone-d5 (mixture of 3a & 3b isomers) is the deuterium labeled 3-Hydroxy tibolone.
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Cidofovir diphosphate-13C3
0 ImagesCat. No.: HY-131606SCidofovir diphosphate-13C3 is the 13C-labeled Cidofovir diphosphate (HY-131606). Cidofovir diphosphate is the intracellular active metabolite of Cidofovir (HY-17438) and its oral prodrug Brincidofovir (HY-14532). By inhibiting viral DNA polymerase (Ki ≈ 76.3 μM), cidofovir diphosphate is widely used in studies on double-stranded DNA virus infections, including cytomegalovirus (CMV), adenovirus (AdV), and poxviruses (such as monkeypox and molluscum contagiosum virus, MCV).
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2-tert-Butylamino-d9-4-chloro-6-cyclopropylamino-1,3,5-triazine
0 Images2-tert-Butylamino-d9-4-chloro-6-cyclopropylamino-1,3,5-triazine is the deuterium labeled 2-tert-Butylamino-4-chloro-6-cyclopropylamino-1,3,5-triazine.
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1-Bromo-3,4-difluorobenzene-d3
0 Images1-Bromo-3,4-difluorobenzene-d3 is the deuterium labeled 1-Bromo-3,4-difluorobenzene.
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Omeprazole sulfone-13C,d3
0 ImagesCat. No.: HY-G0007S1CAS No.: 1261393-28-5Synonyms: Omeprazole sulfone-13C,d3; Omeprazole sulphone-13C,d3Omeprazole sulfone-13C,d3 is the deuterium and 13C labeled Omeprazole sulfone. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair.
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2,2′,4,4′,5-Pentabromo diphenyl ether-13C12
0 ImagesCat. No.: HY-166927SCAS No.: 488710-21-02,2′,4,4′,5-Pentabromo diphenyl ether-13C12 is 13C labeled 2,2′,4,4′,5-Pentabromo diphenyl ether.
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1-Bromononane-d4-1
0 ImagesCat. No.: HY-W014559S3CAS No.: 284474-44-8Synonyms: Nonyl Bromide-d41-Bromononane-d4-1 is the deuterium labeled 1-Bromononane.
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C18:0-d7 GB4 Ceramide (d18:1/18:0-d7)
0 ImagesCat. No.: HY-167598SC18:0-d7 GB4 Ceramide (d18:1/18:0-d7) is deuterium labeled C18:0 GB4 Ceramide (d18:1/18:0).
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PCDE 37-13C12
0 ImagesCat. No.: HY-166963SSynonyms: 3,4,4′-Trichloro diphenyl ether-13C12
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Fedratinib-d9
0 ImagesCat. No.: HY-10409SSynonyms: TG-101348-d9; SAR 302503-d9Fedratinib-d9 (TG-101348-d9) is deuterium labeled Fedratinib. Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.
