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Cat. No.: HY-W654377

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Triptolide-d₃(major) (>90%)

Triptolide-d₃ (major) (>90%) is the deuterium labeled Triptolide (HY-32735). Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.

For research use only. We do not sell to patients.

Formula: C₂₀H₂₁D₃O₆
Molecular Weight:363.42

Storage:

Store at room temperature 3 years.

In solvent -80°C, 2 years , -20°C, 1 year

Data Sheet (250 KB)

Triptolide-d₃(major) (>90%) Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All NF-κB Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 38748-32-2
Appearance Solid
Molecular Weight 363.42
Formula C₂₀H₂₁D₃O₆
Color White to off-white
SMILES

O[C@H]1[C@]23O[C@H]2C[C@]4(C5=C(CC[C@@]4([C@@]36O[C@H]6[C@H]7C1(C(C)C)O7)C)C(OC5([2H])[2H])=O)[2H]
Shipping

Room temperature in continental US; may vary elsewhere.