Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-90009BS

cis-Tadalafil-d₃
cis-Tadalafil-d₃ is the deuterium labeled cis-Tadalafil[1].

HY-121467S

Acotiamide-d₆
Acotiamide-d₆ is a deuterium labeled Acotiamide. Acotiamide is an orally active and first-in-class gastroprokinetic agent for the treatment of functional dyspepsia.

HY-30237S

(R)-Roscovitine-d₇
(R)-Roscovitine-d₇ (Seliciclib-d₇; CYC202-d₇) is deuterium-labeled (R)-Roscovitine (HY-30237).

HY-W004681S

5-Hydroxy-2-methylpyridine-d₆		99%
5-Hydroxy-2-methylpyridine-d₆ is the deuterium labeled 5-Hydroxy-2-methylpyridine.

HY-W714205S

Desethyl terbumeton-d₃
Desethyl terbumeton-d₃ is deuterium labeled N2-(Tert-butyl)-6-methoxy-1,3,5-triazine-2,4-diamine.

HY-B0477AS1

Quinapril-d₅ hydrochloride
Quinapril-d₅ hydrochloride (CI-906-d₅) is the deuterium labeled Quinapril hydrochloride. Quinapril hydrochloride (CI-906) is a prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications.

HY-142275S

(-)-Nebivolol-d₄ hydrochloride
(-)-Nebivolol-d₄ (hydrochloride) is the deuterium labeled (-)-Nebivolol hydrochloride.

HY-137255S

Taurolithocholic Acid-3-Sulfate-d₄ disodium
Taurolithocholic Acid-3-Sulfate-d₄ （disodium salt） is the deuterium labeled Taurolithocholic Acid-3-Sulfate.

HY-150661S

3-epi-Calcifediol-¹³C₅
3-Epi-25-hydroxyvitamin D3-¹³C₅ is the ¹³C labeled 3-Epi-25-hydroxyvitamin D3.

HY-113041S

Prostaglandin A2-d₄
Prostaglandin A2-d₄ is the deuterium labeled Prostaglandin A2.

HY-132490S

5-Hydroxy Buspirone-d₈
5-Hydroxy Buspirone-d₈ is the deuterium labeled 5-Hydroxy Buspirone.

HY-18252S3

Avanafil-¹³C₅
Avanafil-¹³C₅ (TA1790-¹³C₅) is ¹³C labeled Avanafil. Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC₅₀ values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis.

HY-W721117

N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine-d₃
N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine-d₃ (Methyl N-acetyl-S-(3-hydroxypropyl)-L-cysteinate-d₃) is the deuterium labeled N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine.

HY-B0833S1

Thiamethoxam-d₃		99.00%
Thiamethoxam-d₃ is the deuterium labeled Thiamethoxam. Thiamethoxam is a broad spectrum neonicotinoid insecticide.

HY-12389S

8-Hydroxy amoxapine-d₈
8-Hydroxy amoxapine-d₈ is the deuterium labeled 8-Hydroxy amoxapine.

HY-N2037AS1

Higenamine-d₄-1 hydrochloride
Higenamine-d₄-1 (Norcoclaurine-d₄-1) hydrochloride is deuterium labeled Higenamine (hydrochloride). Higenamine hydrochloride is a selective LSD1 inhibitor (IC₅₀=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases.

HY-B0965S

Thioridazine 2-Sulfone-d₃
Thioridazine-d₃ 2-Sulfone is the deuterium labeled Thioridazine hydrochloride. Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs).

HY-12772S3

Hydroxy Itraconazole-d₆
Hydroxy Itraconazole-d₆ (R-63373-d₆) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-W015854S

Ethyl methanesulfonate-d₅		99.48%
Ethyl methanesulfonate-d₅ is the deuterium labeled Ethyl methanesulfonate.

HY-142196S

Betamethasone 17-propionate-d₅
Betamethasone 17-propionate-d₅ is the deuterium labeled Betamethasone 17-propionate.

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