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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10875):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118527S
    Fenirofibrate-d6
    Fenirofibrate-d6 is the deuterium labeled Fenirofibrate.
    Fenirofibrate-d<sub>6</sub>
  • HY-W008836S
    (E)-Hex-3-en-1-ol-d2
    (E)-Hex-3-en-1-ol-d2 is deuterated labeled (E)-Hex-3-en-1-ol.
    (E)-Hex-3-en-1-ol-d<sub>2</sub>
  • HY-16504S
    Treprostinil-13C2,d1 Sodium
    Treprostinil-13C2-d1 (Sodium) (UT-15-13C2-d1(sodium)) is deuterium and 13C labeled Treprostinil (sodium). Treprostinil (UT-15) sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
    Treprostinil-<sup>13</sup>C<sub>2</sub>,d<sub>1</sub> Sodium
  • HY-146831S1
    CER3-d3
    CER3-d3 is the deuterium labeled CER3.
    CER3-d<sub>3</sub>
  • HY-W042301S
    Xipamide-d6
    Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE).
    Xipamide-d<sub>6</sub>
  • HY-114703S1
    Eslicarbazepine-d4
    Eslicarbazepine-d4 (BIA 2-194-d4) is deuterium labeled Eslicarbazepine. Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.
    Eslicarbazepine-d<sub>4</sub>
  • HY-W774926
    Permethrin-d6
    Permethrin-d6 (NRDC-143-d6) is deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide and a high selectively inhibitor of the Mitochondrial complex I, found in sediment and water samples. Permethrin shows estrogenic in vivo and anti-estrogenic activity in vitro. Permethrin also acts as a neurotoxin affecting neuron membranes by prolonging Sodium channel activation. Permethrin decreases resistance to bacterial infections in medaka (Oryzias latipes).
    Permethrin-d<sub>6</sub>
  • HY-W011589S
    Ethyl 2-cyano-3,3-diphenylacrylate-d10
    Ethyl 2-cyano-3,3-diphenylacrylate-d10 (Ethyl-2-cyano-3,3-diphenylpropenoate-d10) is deuterium labeled Ethyl 2-cyano-3,3-diphenylacrylate.
    Ethyl 2-cyano-3,3-diphenylacrylate-d<sub>10</sub>
  • HY-W103239S1
    9-(Naphthalen-1-yl)-10-(naphthalen-2-yl)anthracene-d22
    9-(Naphthalen-1-yl)-10-(naphthalen-2-yl)anthracene-d22 is the deuterium labeled 9-(Naphthalen-1-yl)-10-(naphthalen-2-yl)anthracene.
    9-(Naphthalen-1-yl)-10-(naphthalen-2-yl)anthracene-d<sub>22</sub>
  • HY-152056S
    N-Acetyl glufosinate-d3
    N-Acetyl glufosinate-d3 is the deuterium labeled N-Acetyl glufosinate.
    N-Acetyl glufosinate-d<sub>3</sub>
  • HY-90003S
    Tianeptine-d12
    Tianeptine-d12 is a deuterated analog of Tianeptine (HY-90003).Tianeptine is an atypical antidepressant. Tianeptine is a moderate-intensity agonist of the μ-opioid receptor (MOR), and to a lesser extent, is an agonist of the δ-opioid receptor (DOR). Tianeptine is a glutamate modulator that can enhance AMPA receptor and antagonize NMDA receptor. Tianeptine increases sensitivity of the α1 adrenergic receptor, which only manifests in chronic treatment. Tianeptine exerts neuroprotective effects under stress/inflammation-induced conditions, exhibiting anti-inflammatory and antioxidant properties. Tianeptine inhibits MMP-9 by suppressing the PI3K/Akt-mediated NF-κB pathway. Tianeptine can be used to alleviate symptoms of depression and anxiety, but does not cause sedative effects.
    Tianeptine-d<sub>12</sub>
  • HY-132501S
    4'-Hydroxy Toremifene-d6
    4’-Hydroxy Toremifene-d6 is the deuterium labeled 4’-Hydroxy Toremifene.
    4'-Hydroxy Toremifene-d<sub>6</sub>
  • HY-10082S1
    Triapine-d3
    Triapine-d3 (3-AP-d3) is deuterium labeled Triapine. Triapine (3-AP; PAN-811) is a potent inhibitor of the M2 subunit of ribonucleotide reductase (RR), and is a potent radiosensitizer.
    Triapine-d<sub>3</sub>
  • HY-W701834S
    4-Hydroxymethylambrisentan-d5
    4-Hydroxymethylambrisentan-d5 is deuterium-labeled 4-Hydroxymethylambrisentan (HY-W701834).
    4-Hydroxymethylambrisentan-d<sub>5</sub>
  • HY-17469S
    Gimeracil-13C3,15N
    Gimeracil-13C3,15N (Gimestat-13C3,15N) is 13C and 15N labeled Gimeracil. Gimeracil, a component of an oral fluoropyrimidine derivative S-1, inhibits DNA DSB repair and is a potent inhibitor of DPYD (dihydropyrimidine dehydrogenase, DPD).
    Gimeracil-<sup>13</sup>C<sub>3</sub>,<sup>15</sup>N
  • HY-147338S
    5-Methylcytidine 5′-triphosphate-d3 trisodium
    5-Methylcytidine 5′-triphosphate-d3 trisodium is the deuterium labeled 5-Methylcytidine 5’-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5′-triphosphate trisodium can apply in replacing unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells.
    5-Methylcytidine 5′-triphosphate-d<sub>3</sub> trisodium
  • HY-W714228S
    2-(2-Hydroxy-N-(2-(methoxy-d3)ethyl)acetamido)-3-methylbenzoic acid
    2-(2-Hydroxy-N-(2-(methoxy-d3)ethyl)acetamido)-3-methylbenzoic acid is deuterium labeled 2-(2-Hydroxy-N-(2-methoxyethyl)acetamido)-3-methylbenzoic acid.
    2-(2-Hydroxy-N-(2-(methoxy-d<sub>3</sub>)ethyl)acetamido)-3-methylbenzoic acid
  • HY-14773S1
    Mirabegron-d8
    Mirabegron-d8 (YM178-d8) is deuterium labeled Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
    Mirabegron-d<sub>8</sub>
  • HY-152303S
    N6-(4-Methoxybenzyl)adenosine-d3
    N6-(4-Methoxybenzyl)adenosine-d3 is deuterium labeled N6-(4-Methoxybenzyl)adenosine. N6-(4-Methoxybenzyl)adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
    N6-(4-Methoxybenzyl)adenosine-d<sub>3</sub>
  • HY-B0005S
    Toremifene-d6 citrate
    Toremifene-d6 (citrate) is the deuterium labeled Toremifene citrate. Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 μM and 2.6 μM, respectively.
    Toremifene-d<sub>6</sub> citrate