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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N6662S
    (+)-Longifolene-13,d2
    (+)-Longifolene-13C,d2 is the 13C- and deuterium labeled (+)-Longifolene (HY-N6662). (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant.
    (+)-Longifolene-<sup>13</sup>,d<sub>2</sub>
  • HY-W747703
    Hippuric acid-13C6
    Hippuric acid-13C6 (Benzoylglycine-13C6) is 13C labeled Hippuric acid. Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2, MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research. .
    Hippuric acid-<sup>13</sup>C<sub>6</sub>
  • HY-109583S
    4-Oxofenretinide-d4
    4-Oxofenretinide-d4 (4-Oxo-4-HPR-d4) is deuterium labeled 4-Oxofenretinide. 4-Oxofenretinide (4-Oxo-4-HPR) is a metabolite of Fenretinide (HY-15373). 4-Oxofenretinide induces cell growth inhibition in ovarian, breast, and neuroblastoma tumor cell lines. 4-Oxofenretinide causes a marked accumulation of cells in G2-M. 4-Oxofenretinide induces cancer cell apoptosis through caspase-9.
    4-Oxofenretinide-d<sub>4</sub>
  • HY-15414S1
    Vortioxetine-d6
    Vortioxetine-d6 (Lu AA 21004-d6) is the deuterium labeled Vortioxetine (HY-B1490A). Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM), as well as a 5-HT1A agonist and a partial agonist of 5-HT1B (Ki: 15 nM, 33 nM).
    Vortioxetine-d<sub>6</sub>
  • HY-127035S4
    Tristearin-d9
    Tristearin-d9 is the deuterium labeled Tristearin (HY-127035). Tristearin is a triglyceride derived from three units of stearic acid.
    Tristearin-d<sub>9</sub>
  • HY-W005394S
    (±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 hydrochloride
    (±)-1-Amino-2-phenylpropane-1,1,3,3,3-d5 (hydrochloride) is the deuterium labeled 2-Phenylpropan-1-amine hydrochloride.
    (±)-1-Amino-2-phenylpropane-1,1,3,3,3-d<sub>5</sub> hydrochloride
  • HY-113096S
    Prostaglandin D1-d4
    Prostaglandin D1-d4 (PGD1-d4) is deuterium labeled Prostaglandin D1. Prostaglandin D1 is a prostanoid which causes contractile and relaxant on isolated human pial arteries, it is also an inhibitor of ADP-induced platelet aggregation with an IC50 value of 320 ng/ml. Prostaglandin D1 can be used for metabolic research.
    Prostaglandin D1-d<sub>4</sub>
  • HY-W712501
    Methyl 2-hydroxybenzoate-d3
    Methyl-d3 2-hydroxybenzoate is deuterated labeled Methyl 2-hydroxybenzoate.
    Methyl 2-hydroxybenzoate-d<sub>3</sub>
  • HY-132559S
    PD-166285-d4
    PD-166285-d4 is the deuterium labeled PD-166285.
    PD-166285-d<sub>4</sub>
  • HY-133171AS1
    (R)-Norfluoxetine phthalimide-d5
    (R)-Norfluoxetine-d5 Phthalimide (Phenyl-d5) is the deuterium labeled (R)-Norfluoxetine Phthalimide (Phenyl).
    (R)-Norfluoxetine phthalimide-d<sub>5</sub>
  • HY-W012531S2
    2-Hydroxycinnamic acid-d4
    2-Hydroxycinnamic acid-d4 is deuterium labeled 2-Hydroxycinnamic acid. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity.
    2-Hydroxycinnamic acid-d<sub>4</sub>
  • HY-W275481S2
    5-Octyldihydrofuran-2(3H)-one-d7
    5-Octyldihydrofuran-2(3H)-one-d7 is deuterated labeled 5-Octyldihydrofuran-2(3H)-one.
    5-Octyldihydrofuran-2(3H)-one-d<sub>7</sub>
  • HY-121467S1
    Acotiamide-d4
    Acotiamide-d4 (Z-338 (free base)-d4) is deuterium labeled Acotiamide. Acotiamide is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with an IC50 of 1.79 μM. Acotiamide can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory.
    Acotiamide-d<sub>4</sub>
  • HY-18206S2
    Lisinopril-13C5,15N
    Lisinopril-13C5,15N (MK-521-13C5,15N) is 13C and 15N labeled Lisinopril. Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.
    Lisinopril-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N
  • HY-W701918
    Vonedrine-d3 hydrochloride
    Vonedrine-d3 (Phenpromethamine-d3 ) hydrochloride is the deuterium labeled Vonedrine hydrochloride.
    Vonedrine-d<sub>3</sub> hydrochloride
  • HY-B0347S
    Lacidipine-d10
    Lacidipine-d10 is the deuterium labeled Lacidipine. Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker.
    Lacidipine-</sub>d<sub>10</sub>
  • HY-B0188AS
    Mianserin-d3 (hydrochloride)
    Mianserin-d3 hydrochloride is the deuterium labeled Mianserin. Mianserin (Mianserine) is an orally active H1 receptor antagonist. Mianserin can activate κ-opioid receptor and octopamine receptor. Mianserin increases ERK1/2 and CREB phosphorylation, and antagonizes full κ-opioid agonist and Dynorphin A (HY-P1333)-induced MAPK phosphorylation. Mianserin modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin can be used for the research of neurological disease, such as depression and epilepsy.
    Mianserin-d<sub>3</sub> (hydrochloride)
  • HY-146833S
    1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine-d7
    99.0%
    1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine-d7 is deuterium labeled 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine.
    1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine-d<sub>7</sub>
  • HY-17016S3
    Oseltamivir-13C,d3 phosphate
    Oseltamivir-13C,d3 (phosphate) (GS 4104-13C,d3 (phosphate)) is 13C labeled Oseltamivir (phosphate). Oseltamivir phosphate (GS 4104) is a neuraminidase inhibitor recommended for the treatment and prophylaxis of influenza A and B.
    Oseltamivir-<sup>13</sup>C,d<sub>3</sub> phosphate
  • HY-A0082S
    Diphenidol-d10 hydrochloride
    Diphenidol-d10 (hydrochloride) (Difenidol hydrochloride-d10) is deuterium labeled Diphenidol (hydrochloride). Diphenidol hydrochloride (Difenidol hydrochloride) is a non-selective muscarinic M1-M4 receptor antagonist, has anti-arrhythmic activity. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells. Diphenidol hydrochloride can be used in the study of antivertigo and antinausea.
    Diphenidol-d<sub>10</sub> hydrochloride