2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (11061):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y0636R
    Methyl 4-methyl-3-oxopentanoate (Standard)
    Methyl isobutyrylacetate (Standard) is the analytical standard of Methyl isobutyrylacetate. This product is intended for research and analytical applications.
    Methyl 4-methyl-3-oxopentanoate (Standard)
  • HY-101567R
    BMS-986158 (Standard)
    BMS-986158 (Standard) is the analytical standard of BMS-986158 (HY-101567). This product is intended for research and analytical applications. BMS-986158 is a potent BET inhibitor with IC50s of 6.6 and 5 nM in NCI-H211 small cell lung cancer (SCLC) cells and MDA-MB231 triple negative breast cancer (TNBC) cells, respectively.
    BMS-986158 (Standard)
  • HY-W011955R
    8-Cyclopentyl-1,3-dimethylxanthine (Standard)
    8-Cyclopentyl-1,3-dimethylxanthine (Compound 2a) is a selective adenosine A1 receptor antagonist with Kis of 10.9 nM and 1440 nM for A1 receptor and A2 receptor, respectively.
    8-Cyclopentyl-1,3-dimethylxanthine (Standard)
  • HY-W103877R
    2-Cyclohexyl-2-hydroxy-2-phenylacetic acid (Standard)
    2-Cyclohexyl-2-hydroxy-2-phenylacetic acid (Standard) is the analytical standard of 2-Cyclohexyl-2-hydroxy-2-phenylacetic acid. This product is intended for research and analytical applications.
    2-Cyclohexyl-2-hydroxy-2-phenylacetic acid (Standard)
  • HY-116284R
    Methyl β-D-glucopyranoside (Standard)
    Methyl β-D-glucopyranoside (Methyl β-D-glucoside) (Standard) is the analytical standard of Methyl β-D-glucopyranoside. This product is intended for research and analytical applications. Methyl β-D-glucopyranoside is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside).
    Methyl β-D-glucopyranoside (Standard)
  • HY-109058R
    Firibastat (Standard)
    Firibastat (Standard) is the analytical standard of Firibastat. This product is intended for research and analytical applications. Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor (Ki=200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats.
    Firibastat (Standard)
  • HY-W019715R
    trans-4-(Trifluoromethyl)cinnamic acid (Standard)
    trans-4-(Trifluoromethyl)cinnamic acid (Standard) is the analytical standard of trans-4-(Trifluoromethyl)cinnamic acid (HY-W019715). This product is intended for research and analytical applications. trans-4-(Trifluoromethyl)cinnamic acid is a Phenylpropanoids product that can be isolated from the barks of Cinnamomum cassia Presl.
    trans-4-(Trifluoromethyl)cinnamic acid (Standard)
  • HY-A0144R
    Etilefrine (Standard)
    Etilefrine (Standard) is the analytical standard of Etilefrine. This product is intended for research and analytical applications. Etilefrine is a sympathetic nerve agonist and AMPK activator that selectively targets α1/β1 adrenergic receptors. Etilefrine stimulates α1 adrenergic receptors, leading to contraction of vascular smooth muscle and increased peripheral resistance. Etilefrine also stimulates β1 receptors to enhance myocardial contractility and increase heart rate, thereby increasing blood pressure and improving cardiac output. Etilefrine also bidirectionally regulates the AMPK/Akt pathway and modulates the phosphorylation levels. Etilefrine can be used in cardiovascular research, such as postural hypotension, chylothorax, and improving low cardiac output.
    Etilefrine (Standard)
  • HY-B1303AR
    Mebhydrolin (Standard)
    Mebhydrolin (Standard) is the analytical standard of Mebhydrolin. This product is intended for research and analytical applications. Mebhydrolin is a specific histamine H1 receptor antagonist.
    Mebhydrolin (Standard)
  • HY-12533R
    Disopyramide (Standard)
    Disopyramide (Standard) is the analytical standard of Disopyramide. This product is intended for research and analytical applications. Disopyramide (Dicorantil) is a class IA antiarrhythmic agent with efficacy in ventricular and atrial arrhythmias. Disopyramide blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide inhibits HERG encoded potassium channels. Disopyramide also exhibits complex protein binding, and has a potent negative inotropic action.
    Disopyramide (Standard)
  • HY-N1510R
    Kaempferol 3-O-gentiobioside (Standard)
    Kaempferol 3-O-gentiobioside (Standard) is the analytical standard of Kaempferol 3-O-gentiobioside. This product is intended for research and analytical applications. Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. Kaempferol 3-O-gentiobioside possesses activity against α-glucosidase and displays carbohydrate enzyme inhibitory effect with an IC50 of 50.0 μM.
    Kaempferol 3-O-gentiobioside (Standard)
  • HY-105268R
    AzddMeC (Standard)
    AzddMeC (Standard) is the analytical standard of AzddMeC (HY-105268). This product is intended for research and analytical applications. AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1-infected human PBM cells and HIV-1-infected human macrophages, the EC50 values of AzddMeC are 9 nM and 6 nM, respectively. AzddMeC is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    AzddMeC (Standard)
  • HY-Z0380R
    Iluoridine impurity 9 (Standard)
    Methyl 5-(hydroxymethyl)-2-methoxybenzoate (Standard) is the analytical standard of Methyl 5-(hydroxymethyl)-2-methoxybenzoate. This product is intended for research and analytical applications.
    Iluoridine impurity 9 (Standard)
  • HY-100573R
    Necrosulfonamide (Standard)
    Necrosulfonamide (Standard) is the analytical standard of Necrosulfonamide (HY-100573). This product is intended for research and analytical applications. Necrosulfonamide is a MLKL and Gasdermin D (GSDMD) inhibitor, capable of separately inhibiting necroptosis and pyroptosis of cells. Necrosulfonamide does not affect the activation of upstream signals, but specifically inhibits the downstream executor oligomerization step. Necrosulfonamide reduces the expression of the key kinases NLRP3 and caspase-1 involved in necroptosis and pyroptosis, activate the Nrf2 pathway and the downstream antioxidant enzymes, and also downregulates a variety of inflammatory factors. Necrosulfonamide plays significant roles in various diseases such as neurodegenerative diseases (such as Parkinson’s disease), tissue damage and ischemia-reperfusion injury, inflammatory bowel disease, osteoarthritis and fracture repair, and hair loss by regulating two important programmed necrosis pathways.
    Necrosulfonamide (Standard)
  • HY-103210R
    DSP-4 hydrochloride (Standard)
    DSP-4 hydrochloride (Standard) is the analytical standard of DSP-4 hydrochloride (HY-103210). This product is intended for research and analytical applications. DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons.
    DSP-4 hydrochloride (Standard)
  • HY-B1494R
    Picrotoxinin (Standard)
    Picrotoxinin (Standard) is the analytical standard of Picrotoxinin. This product is intended for research and analytical applications. Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits α1β2γ2L GABAA receptor with an IC50 of 1.15 μM.
    Picrotoxinin (Standard)
  • HY-B0159R
    Balofloxacin (Standard)
    Balofloxacin (Standard) is the analytical standard of Balofloxacin. This product is intended for research and analytical applications. Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections.
    Balofloxacin (Standard)
  • HY-109018BR
    Velagliflozin proline hydrate (Standard)
    Velagliflozin proline hydrate (Standard) is the analytical standard of Velagliflozin (proline hydrate) (HY-109018B). This product is intended for research and analytical applications. Velagliflozin proline hydrate is the clinical form of Velagliflozin (HY-109018). Velagliflozin is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations.
    Velagliflozin proline hydrate (Standard)
  • HY-N0444R
    Rubiadin (Standard)
    Rubiadin (Standard) is the analytical standard of Rubiadin (HY-N0444). This product is intended for research and analytical applications. Rubiadin is an orally active free radical scavenger that inhibits the activation of the NF-κB pathway. Rubiadin inhibits osteoclast formation, bone resorption, lipid peroxidation, HBV DNA replication and cancer cell proliferation; reduces pro-inflammatory cytokine levels; induces cancer cell apoptosis; and possesses antifungal, antimalarial, antibacterial and anticonvulsant activities. Rubiadin can be used in the research of osteoporosis, acute inflammation, chronic inflammation, carbon tetrachloride-induced liver injury, Alzheimer's disease, breast cancer, iron overload disorders, hepatitis B virus infection, colon cancer, liver cancer, T-lymphocytic leukemia, cervical cancer, diabetic nephropathy, epileptic seizures, fungal infections, malaria and bacterial infections.
    Rubiadin (Standard)
  • HY-78834R
    Sacubitrilat impurity 34 (Standard)
    [(1R)-2-(Biphenyl-4-yl)-1-formylethyl]carbamic acid tert-butyl ester (Standard) is the analytical standard of [(1R)-2-(Biphenyl-4-yl)-1-formylethyl]carbamic acid tert-butyl ester. This product is intended for research and analytical applications.
    Sacubitrilat impurity 34 (Standard)