1. Immunology/Inflammation
  2. Aryl Hydrocarbon Receptor
  3. AHR agonist 4

AHR agonist 4 (compound 24e) is an agonist of Aryl hydrocarbon receptor (AHR), assocaited with the immune balance of Th17/22 and Treg cells. AHR agonist 4 serves as a lead compound for anti-psoriasis drug, alleviates imiquimod (IMQ)-induced psoriasis-like skin lesion. AHR agonist 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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AHR agonist 4

AHR agonist 4 Chemische Struktur

CAS. Nr. : 2953023-30-6

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Beschreibung

AHR agonist 4 (compound 24e) is an agonist of Aryl hydrocarbon receptor (AHR), assocaited with the immune balance of Th17/22 and Treg cells. AHR agonist 4 serves as a lead compound for anti-psoriasis drug, alleviates imiquimod (IMQ)-induced psoriasis-like skin lesion[1]. AHR agonist 4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Molekulargewicht

282.32

Formel

C14H10N4OS

CAS. Nr.
SMILES

C#CCN1C(/C(NC1=S)=C/C2=NNC3=C2C=CC=C3)=O

Versand

Room temperature in continental US; may vary elsewhere.

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