AIE-Cbz-LD-C7 

AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER)^[1].

AIE-Cbz-LD-C (0, 2, 5, 10, 20, and 30 μM; 24 h) have excellent biocompatibility^[1].
AIECbz-LD-C7 (0.5 μM, 15 min) could aggregate in LDs accurately and light up the LDs with good photostability^[1].
AIE-Cbz-LD-C7 (0.5 μM) can be used to visualize the interplay between LDs and lysosomes during lipophag due to the excellent LD-specificity^[1].
AIE-Cbz-LD-C7 (0.5 μM, 15 min) increases the number of ferroptosis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

510.67

C₃₅H₃₄N₄

2810130-33-5

CCCCCCCN1C2=C(C3=C1C=CC(/C=C/C4=C/C(C5=CC=CC=C5N4CC)=C(C#N)/C#N)=C3)C=CC=C2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Rui Chen, et al. Rational Design of Novel Lipophilic Aggregation-Induced Emission Probes for Revealing the Dynamics of Lipid Droplets during Lipophagy and Ferroptosis. Anal Chem. 2022 Sep 19.  [Content Brief]