ADX/FDX1 Antibody (YA2005)(PBS only)

Cat. No.: HY-P82260A: Data Sheet User Guide for Antibodies
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ADX/FDX1 Antibody (YA2005) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ADX.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

ADX/FDX1 Antibody (YA2005) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ADX.

Host

Rabbit

분자량

Predicted band size: 19 kDa;

Observed band size: 14 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

P10109

Gene ID

2230 [NCBI]

Immunogen

A synthetic peptide of human Adrenodoxin

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Essential for the synthesis of various steroid hormones (PubMed:20547883, PubMed:21636783). Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis (PubMed:20547883, PubMed:21636783). Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783). Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity)

Subcellular Localization：Mitochondrion matrix

Expression：
Tissue_specificity:Highest levels in the adrenal gland (at protein level) . Also detected in kidney and testis (at protein level)

Subunit：Interacts with CYP11A1

Research Field

Signal Transduction

Synonyms

ADX; FDX; LOH11CR1D; FDX1; Ferredoxin 1 antibody; Adrenal ferredoxin antibody

각종 서류

User Guide for Antibodies (1077 KB)