Cytokeratin 18 Antibody (YA6415)(PBS only)

Cat. No.: HY-P86723A: Data Sheet User Guide for Antibodies
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Cytokeratin 18 Antibody (YA6415) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 18.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Cytokeratin 18 Antibody (YA6415) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 18.

Host

Mouse

분자량

Predicted band size: 48 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P05783

Gene ID

3875 [NCBI]

Immunogen

Recombinant human CK18 protein

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-500

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection

Subcellular Localization：Nucleus matrix; Cytoplasm, perinuclear region; Nucleus, nucleolus; Cytoplasm

Expression：
Tissue_specificity:It is expressed in the colon, placenta, and liver, with very weak expression at the external os of the cervix. Increased expression has been observed in breast cancer lymph nodes.

Induction:By IL6/interleukin-6

Subunit：Heterotetramer of two type I and two type II keratins. KRT18 associates with KRT8 (PubMed:10852826, PubMed:24940650). Interacts with PLEC isoform 1C, when in a heterodimer with KRT8 (PubMed:24940650).

Synonyms

K1C18_HUMAN; Keratin, type I cytoskeletal 18; KRT18; CYK18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18(CK-18); Keratin-18(K18); PIG46; Keratin 18;

각종 서류

User Guide for Antibodies (1077 KB)