Cytokeratin 19 Antibody (YA3716)(PBS only)

Art. -Nr.: HY-P84019A: Data Sheet User Guide for Antibodies
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Cytokeratin 19 Antibody (YA3716) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytokeratin 19.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Größe		Verfügbarkeit
50 μL		Angebot einholen
100 μL		Angebot einholen

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung

Beschreibung

Cytokeratin 19 Antibody (YA3716) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Cytokeratin 19.

Host

Mouse

Molekulargewicht

Predicted band size: 42 kDa;

Observed band size: 42 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P08727

Gene ID

3880 [NCBI]

Immunogen

Purified recombinant fragment of human KRT19 aa 115-269.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Reinheit	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle

Expression：
Tissue_specificity:It is expressed in specific basal keratinocyte regions of the deep outer root sheath of hair follicles. It is also found in sweat glands and mammary ducts and secretory cells, bile ducts, gastrointestinal tract, bladder urothelial tissue, oral epithelium, esophagus, and cervical external epithelium (protein level) . It is expressed in specific regions of epidermal basal cells, nipple epidermis, and hair follicles. It is also found in some wall cells of the human umbilical vein and arteries, as well as in the smooth muscle of umbilical vessels. In structures containing dystrophin and spectroscopylin, muscle fibers aggregate in sarcomeres within the sarcoplasm of the sarcolemma.

Subunit：Heterotetramer of two type I and two type II keratins. Interacts with PNN and the actin-binding domain of DMD. Interacts with HCV core protein

Synonyms

K19; CK19; K1CS; MGC15366

Dokumentation

User Guide for Antibodies (1077 KB)