DLX1 Antibody (YA7839)(PBS only)

Cat. No.: HY-P88155A: Fiche technique User Guide for Antibodies
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DLX1 Antibody (YA7839) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to DLX1.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

DLX1 Antibody (YA7839) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to DLX1.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P56177

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-255 of human DLX1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Pureté	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (By similarity). Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity)

Subcellular Localization：Nucleus

Expression：
Tissue_Specificity: Expressed in hematopoietic cell lines

Isoforms & Post-Translational Modification：P56177 has two isomers: P56177-1: 27320 Da (predicted); P56177-2: 13521 Da (predicted).

Subunit：Interacts with SMAD4 (via homeobox DNA-binding domain) (PubMed:14671321)

Synonyms

distal-less homeo box 1; distal-less homeobox 1

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/huh-7-cell.html [Content Brief]