Dopamine Transporter Antibody (YA7711)

Art. -Nr.: HY-P88026: Data Sheet User Guide for Antibodies
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Dopamine Transporter Antibody (YA7711) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dopamine Transporter.

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100 μL		Angebot einholen

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung

Beschreibung

Dopamine Transporter Antibody (YA7711) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dopamine Transporter.

Host

Rabbit

Clonality

Recombinant

Molekulargewicht

Predicted band size: 68 kDa;

Observed band size: 50 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Predicted Reactivity

Human

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

Q01959

Immunogen

A synthesized peptide derived from human Dopamine transporter

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:50-100
IP IP: Immunoprecipitation	1:20-50

Sensitivity	Endogenous	Reinheit	affinity purified by Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Mediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:11093780, PubMed:1406597, PubMed:15505207, PubMed:19478460, PubMed:39112701, PubMed:39112703, PubMed:39112705, PubMed:8302271). Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling (By similarity)

Subcellular Localization：Cell membrane,Cell projection, neuron projection,Cell projection, axon

Expression：
Tissue_Specificity: Highly expressed in substantia nigra (PubMed:7637582). Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level) (PubMed:17296554). Expressed in the striatum (at protein level) (PubMed:17296554)

Isoforms & Post-Translational Modification：Q01959: 620 amino acids, molecular weight 68495 Da.

Subunit：Monomer (PubMed:39112701, PubMed:39112703, PubMed:39112705)

Dokumentation

User Guide for Antibodies (1077 KB)