Epoxide Hydrolase 1 Antibody (YA2895)(PBS only)

Cat. No.: HY-P83150A: Data Sheet User Guide for Antibodies
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Epoxide Hydrolase 1 Antibody (YA2895) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Epoxide Hydrolase 1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Epoxide Hydrolase 1 Antibody (YA2895) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Epoxide Hydrolase 1.

Host

Rabbit

Molecular Weight

Predicted band size: 63 kDa;

Observed band size: 63 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

P34913

Gene ID

2052 [NCBI]

Immunogen

A synthetic peptide of human EPHX2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Bifunctional enzyme (PubMed:12574510). The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides (PubMed:12574510, PubMed:12869654, PubMed:22798687). Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides (By similarity). Also determines steady-state levels of physiological mediators (PubMed:12574510, PubMed:12869654, PubMed:21217101, PubMed:22798687); Bifunctional enzyme (PubMed:12574510). The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid and 12-phosphonooxy-octadec-9E-enoic acid (PubMed:12574510). Has phosphatase activity toward lyso-glycerophospholipids with also some lower activity toward lysolipids of sphingolipid and isoprenoid phosphates (PubMed:22217705, PubMed:22387545)

Subcellular Localization：Cytoplasm; Peroxisome

Expression：
Induction:By compounds that cause peroxisome proliferation such as clofibrate, tiadenol and fenofibrate

Isoforms & Post-Translational Modification：P34913 has 3 isomers: P34913-1: 62616 Da (predicted); P34913-2: 57123 Da (predicted); P34913-3: 55626 Da (predicted).
The N-terminus is blocked;The covalent modification of cysteine by 15-deoxy-Delta12,14-prostaglandin-J2 is autocatalytic and reversible. It may occur as an alternative to other cysteine modifications, such as S-nitrosylation and S-palmitoylation (Probable)

Subunit：Homodimer

Research Field

Cell Biology

Synonyms

CEH; SEH; ABHD20

Documentation

User Guide for Antibodies (1077 KB)