FCAMR/CD351 Antibody (YA7132)

Cat. No.: HY-P87444: Data Sheet User Guide for Antibodies
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FCAMR/CD351 Antibody (YA7132) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FCAMR/CD351.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

FCAMR/CD351 Antibody (YA7132) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FCAMR/CD351.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 57.1kDa;

Species Reactivity

Human

SwissProt ID

Q8WWV6

Immunogen

Purified recombinant fragment of human CD351 (AA: extra 221-450) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	Purity	affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Functions as a receptor for the Fc fragment of IgA and IgM. Binds IgA and IgM with high affinity and mediates their endocytosis. May function in the immune response to microbes mediated by IgA and IgM

Subcellular Localization：Cell membrane

Expression：
Tissue_Specificity: Expressed by mesangial cells
Induction: Up-regulated by IFNG/IFN-gamma in mesangial cells

Isoforms & Post-Translational Modification：Q8WWV6 has 5 isomers: Q8WWV6-1: 57144 Da (predicted); Q8WWV6-2: 24861 Da (predicted); Q8WWV6-4: 46749 Da (predicted); Q8WWV6-5: 57788 Da (predicted); Q8WWV6-6: 62178 Da (predicted).
N-glycosylated

Subunit：Interacts with IGHM; this interaction facilitates the endocytosis of IgM-coated microbes or IgM-antigen immune complexes

Database

SwissProt: SwissProt: Q8WWV6

Documentation

User Guide for Antibodies (1077 KB)